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Researchers develop universal MHC molecules that can be produced rapidly at scale

Class I major histocompatibility complex (MHC-I) proteins play an essential role in the immune system of all jawed vertebrates. The MHC-I displays peptide fragments of proteins from within the cell on the cell surface, "presenting" them to the immune system, which is constantly scanning the body for foreign or toxic antigens. ....

University Of Pennsylvania , United States , George Burslem , Michaelc Young , Claireh Woodward , Nikolaosg Sgourakis , Yi Sun , Sgourakis Lab , Proceedings Of The National Academy Sciences , National Academy , Associate Professor , Genomic Medicine ,

CHOP Researchers Develop Universal MHC Molecules that Can be Produced Rapidly at Scale

/PRNewswire/ Class I major histocompatibility complex (MHC-I) proteins play an essential role in the immune system of all jawed vertebrates. The MHC-I. ....

United States , University Of Pennsylvania , Fox Chase Cancer Center , New Jersey , Michaelc Young , Claireh Woodward , George Burslem , Nikolaosg Sgourakis , Yi Sun , Sgourakis Lab , Care Network , Proceedings Of The National Academy Sciences , National Academy , Associate Professor , Genomic Medicine ,

CHOP Researchers Develop Universal MHC Molecules that Can be Produced Rapidly at Scale

The molecules open the door for development of immunotherapies that are truly universal and work across HLA types, regardless of patient ancestr. ....

University Of Pennsylvania , United States , Fox Chase Cancer Center , New Jersey , Nikolaosg Sgourakis , Claireh Woodward , George Burslem , Yi Sun , Michaelc Young , Sgourakis Lab , Proceedings Of The National Academy Sciences , Care Network , National Academy , Associate Professor , Genomic Medicine ,

Eight Penn Medical School researchers win 'High-Risk, High-Reward' grants from the NIH

Eight Penn Medical School researchers win 'High-Risk, High-Reward' grants from the NIH
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United States , Nina Dilworth , Donita Brady , Luca Busino , Terence Gade , Chengcheng Jin , Sophia Leung , Eric Witze , George Burslem , Amelia Escolano , Bushra Raj , National Institute Of Health , Upenn Medical School , Perelman School Of Medicine , Transformative Research Award , National Institute Of Health High , Mark Foundation For Cancer Research , Penn Perelman School Of Medicine , Tsinghua University , Eight Penn Medical School , Perelman School , National Institute , Medical School , Probe Enabled Activity Reporting , New Innovator Award , Endeavor Award ,