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CHOP researchers unlock 3D structure of crucial protein for cancer therapy

Chimeric Antigen Receptors (CARs) have opened up an exciting new field of therapeutic advancements for rare and difficult-to-treat cancers, as they have the ability to deliver targeted therapies that can kill tumor cells.

Philadelphia
Pennsylvania
United-states
University-of-pennsylvania
United-kingdom
American
Nikolaosg-sgourakis
Johnm-maris
National-cancer-institute
Mark-foundation
American-association-for-cancer-research

CHOP Researchers Enhance CAR Therapy with Deep Biology Links

CHOP Researchers Enhance CAR Therapy with Deep Biology Links
miragenews.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from miragenews.com Daily Mail and Mail on Sunday newspapers.

Philadelphia
Pennsylvania
United-states
New-jersey
University-of-pennsylvania
United-kingdom
American
Nikolaosg-sgourakis
Johnm-maris
Entertainment-industry-foundation
Neuroblastoma-research

Researchers discover deep structural biology connections that help improve CAR therapy

Researchers discover deep structural biology connections that help improve CAR therapy
medicalxpress.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from medicalxpress.com Daily Mail and Mail on Sunday newspapers.

University-of-pennsylvania
Pennsylvania
United-states
Philadelphia
Johnm-maris
Nikolaosg-sgourakis
Nikolaos-sgourakis
Neuroblastoma-research
Sgourakis-lab
Associate-professor
Genomic-medicine
Giuliod-angio-chair

Deep Structural Biology Links Boost CAR Therapy: Study

Deep Structural Biology Links Boost CAR Therapy: Study
miragenews.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from miragenews.com Daily Mail and Mail on Sunday newspapers.

University-of-pennsylvania
Pennsylvania
United-states
United-kingdom
Philadelphia
American
John-maris
Nikolaosg-sgourakis
Johnm-maris
Nikolaos-sgourakis
Amarachi-onwuka
Cancer-research-united-kingdom

CHOP researchers engineer stable, universal MHC-I molecules in a shorter timeframe

Class I major histocompatibility complex (MHC-I) proteins play an essential role in the immune system of all jawed vertebrates. The MHC-I displays peptide fragments of proteins from within the cell on the cell surface, "presenting" them to the immune system, which is constantly scanning the body for foreign or toxic antigens.

University-of-pennsylvania
Pennsylvania
United-states
Fox-chase-cancer-center
Philadelphia
Michaelc-young
George-burslem
Lily-ramsey
Nikolaosg-sgourakis
Yi-sun
Claireh-woodward
Sgourakis-lab

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