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Lowering the reaction: Tackling biomedical implant immune responses

Why are some implants rejected by our bodies? The cells react by building a fibrotic capsule that surrounds the implant in an attempt to shield it. ....

Geoffrey Gurtner , University Of Arizona College Medicine , Arizona College , Nature Biomedical Engineering ,

Foreign body

An immune reaction called the foreign body response – where the body encapsulates the implant in sometimes painful scar tissue – is a key driver of implant rejection. Developing treatments that target the mechanisms driving foreign body responses could improve the design and safety of biomedical implants. ....

Jagan Padmanabhan , Dharshan Sivaraj , Geoffrey Gurtner , Biomedical Engineering , University Of Arizona Tucson , Nature Biomedical Engineering , Kellen Chen ,