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Researchers determine the structure of nanomachine essential for functioning of mTOR


Researchers determine the structure of nanomachine essential for functioning of mTOR
The principle that form follows function does not only apply to design and architecture. It also applies to biology. Every organism is a universe that lives thanks to the activities of tens of thousands of nanomachines, whose functions depend on their forms. Biologists say macromolecular complexes instead of nanomachines and structure instead of form, but the idea is the same: know the form and you will understand the function. Now, a group at the Spanish National Cancer Research Centre (CNIO) has helped determine the structure of a nanomachine essential for the functioning of another, mTOR, which plays fundamental roles in cancer and nutrition, aging, and other vital processes in the body. ....

Mohinder Pal , Laurenceh Pearl , Chrisostomos Prodromou , Emily Henderson , Spanish National Cancer Research Centre , Stability Centre , Damage Response Group , University Of Sussex United Kingdom , Cell Reports , Genome Damage , United Kingdom , Structural Biology , Macromolecular Complexes , Response Group , Centro Nacional De Investigaciones Oncol , மொிந்தேர் நண்பா , எமிலி ஹென்டர்சன் , ஸ்பானிஷ் தேசிய புற்றுநோய் ஆராய்ச்சி மையம் , ஸ்திரத்தன்மை மையம் , சேதம் பதில் குழு , பல்கலைக்கழகம் ஆஃப் சசெக்ஸ் ஒன்றுபட்டது கிஂக்டம் , செல் அறிக்கைகள் , மரபணு சேதம் , ஒன்றுபட்டது கிஂக்டம் , கட்டமைப்பு உயிரியல் , பதில் குழு ,