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Does SARS-CoV-2's ability to infect humans stem from its evolutionary past?

Study challenges the hypothesis of genetic recombination in SARS-CoV-2's evolution, suggesting its ancestral virus already possessed human-infecting traits, based on analyses of over 100 viral genomes. ....

Saudi Arabia , Sarbecovirus Khosta , Global Initiative On Sharing All Influenza Data , Scientific Reports , Image Credit , Brief History , Family Coronaviridae , Middle East , Ancestral Conversion Graphs , Ancestral Recombination Graphs , Global Initiative , Sharing All Influenza Data , Coronavirus Disease Covid 19 , Ars Cov 2 , Amino Acid , Covid 19 , Genetic Recombination , Evere Acute Respiratory , Evere Acute Respiratory Syndrome ,

Cre-LoxP: Issues Modulating Genes in the Immune System

Cre-loxP, a powerful tool for preclinical cancer research, possesses intrinsic pitfalls that can alter result accuracy according to an editorial paper in Oncoscience. ....

Piotr Czarnota , Bert Omalley , Jaroslaw Cisowsk , Berto Malley , Sark Three , Cre Loxp , Immune System , Gene Knockout , Regulatoryt Cells , Gene Expression , Genetic Recombination , Crispr Cas9 ,

New tool provides insight into the developmental history of certain immune cells

A new tool that can uncover the developmental history of certain immune cells is now freely available worldwide. The tool provides insights into the stages that immune cells go through in a healthy individual and how this can be impacted in disease. ....

United Kingdom , Sarah Teichmann , Lily Ramsey , Kelvin Zewen Tuong , Menna Clatworthy , Wellcome Sanger Institute , University Of Queensland , University Of Cambridge , Human Cell Atlas , Nature Biotechnology , Chenqu Suo , First Author , Wellcome Sanger , B Cell , Dwell Development , Genetic Recombination , Immune Response , Immune System , Natural Killer Cells , Single Cell Genomics ,

Study detects ten avian influenza A viruses in poultry from four provinces in China

Researchers identified 10 avian influenza A(H5N6) viruses in poultry from four Chinese provinces, with immune-evasion and complex genetic recombination potential. ....

World Health Organization , Emerging Infectious Diseases , Novel Reassortant Avian Influenza , Avian Influenza , Genetic Recombination , Infectious Diseases ,

SARS-CoV-2 recombinant isolated from chronic COVID-19 patient

A new research paper in the journal Viruses reports the isolation of a recombinant strain in a patient infected with the virus for over a year. ....

United States , United Kingdom , Sequential Appearance , Two Major , Chronically Infected Immunocompromised , Image Credit , Coronavirus Disease Covid 19 , Ars Cov 2 , Genetic Recombination , Ibonucleic Acid , Evere Acute Respiratory , Evere Acute Respiratory Syndrome ,