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Controlling Cholesterol in Microglia Reduces Chronic Pain


Controlling Cholesterol in Microglia Reduces Chronic Pain
by Angela Mohan on 
May 11, 2021 at 2:57 PM
Journal of Experimental Medicine.
The study was a collaboration between the laboratories of senior study author Yury Miller, MD, PhD, professor of medicine, and Tony Yaksh, PhD, professor of anesthesiology and pharmacology, both at UC San Diego School of Medicine. Miller studies cholesterol metabolism and cardiovascular and neuro inflammation. Yaksh specializes in neuropathic pain.
It was truly gratifying to work at the intersection of two disciplines and identify the role cholesterol plays in activation of microglia immune cells of the spinal cord and regulation of chronic pain, said first author Juliana Navia-Pelaez, PhD, a postdoctoral fellow in Miller s lab. ....

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