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Functional gastrointestinal disorders (FGID) are common disorders associated with persistent and recurrent gastrointestinal (GI) symptoms. Several studies have indicated that stress and psychological difficulties make FGID worse. This article focuses on the physiological and psychological aspects of FGID. ....
Immune checkpoint inhibitors (ICIs), such as anti-CTLA-4 antibodies, are widely used in cancer immunotherapy. CTLA-4 blockers such as Yervoy (ipilimumab, Bristol Myers Squibb Co.) stimulate antitumoral immune responses, but may also induce toxicity, such as colitis, a common immune-related adverse event that can lead to treatment discontinuation. ....