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COVID-19 infection may promote aortic aneurysms and new treatment may slow its growth

The intravenous delivery of immune-modulating cells may someday slow the expansion of bulges in the aorta, known as abdominal aortic aneurysms. ....

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New Treatment May Shrink Abdominal Aortic Aneurysm, COVID May Speed Growth

New Treatment May Shrink Abdominal Aortic Aneurysm, COVID May Speed Growth
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Abdominal aortic aneurysm: new treatment may

Abdominal aortic aneurysm, a weakening and ballooning of the aorta, the largest blood vessel in the body, may result in a life-threatening rupture.
In a small, preliminary study examining a potential treatment to keep small abdominal aortic aneurysms from growing to a dangerous size, intravenous administration of immune-modulating cells resulted in a significant decrease in pro-inflammatory cells, and with higher doses, there was a decrease in aneurysm size. ....

United States , Stanford University , Jia Guo , Makoto Samura , Michael Ingram , Ravi Mylvaganan , Ronaldl Dalman , Paul Terito , Humraazs Samra , Kristin Wancyzk , Baohui Xu , Elsar Chidester , Michaelp Murphy , Mithun Sinha , Ashley Gutwein , Raghu Motaganahalli , Toru Ikezoe , Katherin Leckie , Anush Motaganahalli , Sihai Zhao , Indiana University School Of Medicine , Stanford Research Repository Database , American Heart Association , Cryptic Masons Medical Research Foundation , Council On Genomic , Veterans Administration ,

Immune-modulating cells may slow small AAA progression; COVID-19 may quicken it

IV allogeneic mesenchymal stromal cells may reduce inflammatory response and thereby reduce the progression of small abdominal aortic aneurysms, a speaker reported.A second study presented at the American Heart Association’s Vascular Discovery: From Genes to Medicine Scientific Sessions demonstrated that SARS-CoV-2 infection — in addition to other risk factors — could cause ....

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Cereno Scientific to present new preclinical data for drug candidate CS585 at scientific conference Vascular Discovery 2023: From Genes to Medicine

Cereno Scientific today announced that an abstract on the preclinical drug candidate CS585 has been accepted as an oral presentation at the scientific conference Vascular Discovery. | April 21, 2023 ....

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