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Sotorasib Provides Consistent Clinical Benefit Over Docetaxel in Key Co-Alteration Subgroups of KRAS G12C+ NSCLC

Sotorasib provided consistent benefit over docetaxel in the majority of key prespecified molecularly defined subsets of patients with pretreated KRAS G12C–mutated non–small cell lung cancer enrolled to the phase 3 CodeBreaK 200 trial. ....

United States , Sotorasib Lumakras , Ferdinandos Skoulidis , Department Of Thoracic Head , University Of Texas Md Anderson Cancer Center , Neck Medical Oncology , Cancer Center , Kras G12c , Non Small Cell Lung Cancer , Asco Annual Meeting , Codebreak 200 Trial ,

Dr Skoulidis on the Methods of Analyzing KRAS G12C Inhibitor Efficacy in NSCLC

Ferdinandos Skoulidis, MD, PhD, MRCP, discusses the methods utilized in a retrospective study that investigated molecular determinants of KRAS G12C inhibitor efficacy in patients with advanced non–small cell lung cancer.
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United States , Ferdinandos Skoulidis , University Of Texas Md Anderson Cancer Center , Department Of Thoracic Head , Neck Medical Oncology , Cancer Center , The University Of Texas Md Anderson Cancer Center , Onclive Tv , Lung Cancer ,