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Aspirin May Prevent Colorectal Cancer by Revving Up Immunity

New uses for aspirin … and other research

Ann Robinson reviews the latest research The ancient Sumerians and Egyptians used willow bark containing salicylates to treat pain and fevers more than 3500 years ago. In 1897, Bayer chemist Felix Hoffmann synthesised the first aspirin tablet, and 70 years later John Vance explained that it works by inhibiting prostaglandins. Today, aspirin remains one of the most widely used drugs worldwide and new indications for its use can still get researchers excited. This preliminary phase 2 trial of 80 adults with metabolic dysfunction-associated steatotic liver disease (MASLD) found that six months of taking daily, low dose aspirin (81 mg) significantly reduced their total hepatic fat quantity compared with placebo (−6.6% v 3.6%, mean difference −10.2%) and increased the number of participants achieving 30% hepatic fat reduction (42.5% v 12.5%). The rationale is that reducing hepatic fat prevents inflammation, fibrosis, and eventual progression to liver failure. But further study in a

36 Bits of Trivia to Fertilize Your Brainstem

Facts of the Matter: Benefits of popular painkiller, blood thinner balance risks

For more than 100 years the safest, most effective, least expensive and widest-ranging drug known to man has been available to ease headaches, stop inflammation and lower fever.

Deborah Turbeville's captivating fashion photography remembered in new book

Deborah Turbeville made an ever-lasting mark on fashion photography; now her photocollages are celebrated in alluring new book