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Belzutifan Improves Symptoms and Extends Time to Treatment Deterioration in Advanced RCC

Belzutifan treatment led to improved quality of life outcomes vs treatment with everolimus in patients with advanced renal cell carcinoma. ....

Thomas Powles , Barts Cancer Center , Queen Mary University Of London , Functional Assessment , Queen Mary University , Quality Of Life Outcomes , Patients With Advanced Renal Cell Carcinoma , Litespark 005 Trial ,

Drug-eluting scaffold superior to angioplasty for infrapopliteal artery disease

1. In this randomized controlled trial, for patients with chronic limb-threatening ischemia (CLTI) due to infrapopliteal artery disease (IAD), a drug-eluting resorbable scaffold was superior to angioplasty in reducing the risk of vascular events. 2. There was no significant difference in the adverse events between the drug-eluting resorbable scaffold and angioplasty groups. Evidence Rating Level: ....

Minute Medicine Inc , Rating Level , Confidence Interval , Chronic Disease , Drug Eluting Scaffold , Infrapopliteal Artery Disease , Limb Threatening Ischemia , Vascular Surgery ,

Novel Therapies for Advanced RCC: LITESPARK-005 and Treatment Sequencing

Leading oncologists discuss advanced treatment options for patients with progressing renal cell carcinoma (RCC), focusing on the promising results from LITESPARK-005 and treatment sequencing strategies. ....

Optimizing Therapy , Advanced Renal Cell Carcinoma , Renal Cell Carcinoma , Advanced Rcc , Metastatic Rcc , Kidney Cancer , Novel Therapies , Litespark 005 , Treatment Sequencing , Vegf Tki , Immune Checkpoint Inhibitors , Progression Free Survival , Overall Survival , Clinical Trials , Treatment Options , Pd 1 Inhibitors , Pd L1 Inhibitors , Quality Of Life , Performance Status ,

Sequencing and Second-Line Therapy in RCC: Patient Scenario

Expert oncologists discuss the challenges and considerations in choosing second-line therapy for a patient with metastatic renal cell carcinoma (RCC) in a case-based context. ....

Optimizing Therapy , Advanced Renal Cell Carcinoma , Second Line Therapy , Patient Scenario , Renal Cell Carcinoma , Metastatic Rcc , Kidney Cancer , Case Based Discussion , Adjuvant Therapy , Immune Therapy , Metastatic Kidney Cancer , Treatment Choice , Clinical Trial , Tki Based Therapy , Adjuvant Treatment , Risk Factors , Quality Of Life , Therapy Sequence , Drug Interaction ,

HIF-2α inhibitor belzutifan significantly reduces progression of clear cell renal cell carcinoma

Belzutifan significantly reduced the risk of progression of clear cell renal cell carcinoma (ccRCC), the most common type of kidney cancer, in patients previously treated with immune checkpoint inhibitors and anti-angiogenic therapies compared with everolimus in a phase 3 clinical trial. ....

Danielle Ellis , Tonik Choueiri , Genitourinary Cancer At Dana Farber Institute , Congress On , Merck Sharp Dohme , European Society For Medical Oncology , Lank Center , Genitourinary Cancer , Dana Farber Cancer Institute , European Society , Medical Oncology , Von Hippel Landau , Nobel Prize , Dana Farber Cancer , Merck Sharp , Kidney Cancer , Clinical Trial , Renal Cell Carcinoma ,