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Expert oncologists discuss the challenges and considerations in choosing second-line therapy for a patient with metastatic renal cell carcinoma (RCC) in a case-based context.

Optimizing therapyAdvanced renal cell carcinomaSecond line therapyPatient scenarioRenal cell carcinomaMetastatic rccKidney cancerCase based discussionAdjuvant therapyImmune therapyMetastatic kidney cancerTreatment choiceClinical trialTki based therapyAdjuvant treatmentRisk factors