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Ketone supplement boosts efficacy of prostate cancer immunotherapy

Adding a pre-ketone supplement -; a component of a high-fat, low-carb ketogenic diet -; to a type of cancer therapy in a laboratory setting was highly effective for treating prostate cancer, researchers from the University of Notre Dame found. ....

United States , University Of Notre Dame , Xin Lu , Yini Zhu , Jamesh Schofield , Mary Jo Boler , Jun Li , Maxim Manyak , Xuemin Lu , Guoqiang Liu , Zacharyt Schafer , Sharif Rahmy , Sean Murphy , National Institutes Of Health , Boler Parseghian Center , American Institute For Cancer Research , Department Of Biological Sciences , Cancer Research , Translational Sciences Institute , Boler Family Foundation , Center At Notre Dame , Department Of Defense , Notre Dame , Mary Jo Boler Collegiate Associate Professor , Biological Sciences , Dailin Gan ,

Immune cells play a bigger role in high blood pressure than previously thought, opening doors for new treatments

A review in Nature Reviews Nephrology presents the association between immune cells and the development of hypertension, suggesting potential new therapeutic targets to mitigate the disease by managing inflammation. ....

United States , Meletios Verras , Nature Reviews Nephrology , Blood Pressure , High Blood Pressure ,

Immune dysfunction mechanism discovered in stroke and heart attack patients

Every year, between 250,000 and 300,000 people in Germany suffer from a stroke or heart attack. ....

Matthias Gunzer , Vikramjeet Singh , Head Of The Biospectroscopy Department , Institute Of Experimental Immunology , Journal Nature Cardiovascular Research , Leibniz Institute For Analytical Sciences , Leibniz Institute For Analytical Sciences In Dortmund , University Hospital , Leibniz Institute , Analytical Sciences , Journal Nature Cardiovascular , Experimental Immunology , Biospectroscopy Department , Stroke Immunology Unit , Heart Attack , Blood Vessels ,

Understanding how stress accelerates cancer spread

Stress is inevitable. But too much of it can be terrible for our health. Chronic stress can increase our risk for heart disease and strokes. ....

Mikala Egeblad , Van Aelst , Linda Van Aelst , Cold Spring Harbor Laboratory , Spring Harbor , Adjunct Professor , Cell Biology , Heart Disease , Lung Cancer ,

Females' immune system edges out males but at a cost of higher autoimmune risk

A review article highlights how two X chromosomes in females influence immune system composition and function, leading to faster infection clearance and stronger vaccination responses but also a higher risk of autoimmune diseases. ....

Ustyna Shevchuk , Nature Reviews Immunology , Immune System , Anti Inflammatory , Autoimmune Disease , Lupus Erythematosus , Systemic Lupus Erythematosus , Sex Chromosome ,