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Mount Sinai Trial Shows RNA Inhibitor Safely Lowers Cholesterol

Mount Sinai Trial Shows RNA Inhibitor Safely Lowers Cholesterol
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RNA Inhibitor Safely Lowers Cholesterol in Clinical Trial

RNA Inhibitor Safely Lowers Cholesterol in Clinical Trial
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RNA inhibitor is shown safe and effective in reducing a wide range of cholesterol and triglyceride levels in the blood

A small interfering RNA (siRNA) investigational therapy that inhibits a gene involved in lipoprotein metabolism has been shown in a clinical trial led by Mount Sinai researchers to significantly reduce levels of different types of cholesterol and triglycerides in individuals with mixed hyperlipidemia, a condition in which fats build up in the blood. ....

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Post-hoc Analysis Offers Hope for Novel Cholesterol Drug

Vupanorsen disappointed on triglyceride and non-HDL cholesterol reduction in TRANSLATE-TIMI 70, but post-hoc data on VLDL and remnant cholesterol point to a role for the class if not the drug, experts say. ....

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