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Why the Sudden Onset of Severe Abdominal Pain, Then a Rash?


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A 53-year-old woman presents to an emergency department in London after leaving her workplace due to what she describes as extremely severe and burning pain in her left upper abdomen, radiating to her left back. She explains that she has never experienced these symptoms before, nor has she had any previous acute illness requiring hospitalization.
Her past medical history includes indigestion and regurgitation, which her physician is investigating. Her family history offers no additional relevant information, and findings of a physical examination are unremarkable.
Her vital signs are within normal range, and findings of a general examination are unremarkable. However, palpation of her abdomen reveals a very tender, warm left hypochondrial region with hypersensitivity; there is no evidence of enlarged organs or visible skin lesions. ....

City Of , United Kingdom , Herpes Zoster , Mimicking Acute , Disorder Of Skin , Eruption Of Skin , Infectious Disease , நகரம் ஆஃப் , ஒன்றுபட்டது கிஂக்டம் , பிரதிபலித்தல் எடுப்போசை , கோளாறு ஆஃப் தோல் , வெடிப்பு ஆஃப் தோல் , தொற்று நோய் ,

Young Hidradenitis Suppurativa Patients See Lags in Care


There s some room for improvement in diagnosing pediatric hidradenitis suppurativa (HS), researchers suggested.
In an international cross-sectional analysis of 481 patients diagnosed with HS, the average age of diagnosis came about 2 years after the average age of disease onset (14.4 and 12.5 years, respectively), according to Irene Lara-Corrales, MD, of the University of Toronto, and colleagues.
Among adolescents, the inflammatory skin condition most often presented with a cyst or abscess, accounting for about half of the first signs and symptoms, they stated in
The second and third most common initial symptoms of the debilitating disorder were pain and tenderness (25%), followed by papules and pustules (24%). ....

New York , United States , Irene Lara Corrales , Andrea Zaenglein , Lauren Orenstein , Joslyn Kirby , University Of Toronto , Penn State Hershey Medical Center , Emory University School Of Medicine , Emory University School , New York City , Hidradenitis Suppurativa , Disorder Of Skin , Eruption Of Skin , புதியது யார்க் , ஒன்றுபட்டது மாநிலங்களில் , ஐரீந் லாரா கறல்ஸ் , லாரன் ஒரென்சித்தேன் , ஜோஸ்லின் கர்பீ , பல்கலைக்கழகம் ஆஃப் டொராண்டோ , பென் நிலை ஹெர்ஷே மருத்துவ மையம் , உணர்ச்சி பல்கலைக்கழகம் பள்ளி ஆஃப் மருந்து , உணர்ச்சி பல்கலைக்கழகம் பள்ளி , புதியது யார்க் நகரம் , கோளாறு ஆஃப் தோல் , வெடிப்பு ஆஃப் தோல் ,

Radiotherapy's Role in Metastatic Prostate Cancer Clarified


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Adding radiation therapy to standard treatment improved failure-free survival (FFS) and overall survival for prostate cancer patients with only a few bone metastases, an exploratory analysis of the multi-arm, multi-stage STAMPEDE trial found.
Among the nearly 2,000 men in the study, adding radiation to mostly androgen deprivation therapy (ADT) improved both FFS (HR 0.57, 95% CI 0.47-0.70) and overall survival (HR 0.62, 95% CI 0.46-0.83) in those with only non-regional lymph node metastasis or with fewer than three bone lesions and no visceral metastases, reported Noel Clarke, MBBS, of the Christie NHS Foundation Trust in Manchester, England, and colleagues.
Patients either with visceral metastasis or four or more bone lesions still had improved FFS (HR 0.87, 95% CI 0.76-0.99, ....

North Carolina , United States , Duke University , Bridget Koontz , Noel Clarke , Thomas Hope , Ian Ingram , Duke University School Of Medicine , University Of California San Francisco , Foundation Trust In Manchester , Duke University School , California San Francisco , Medpage Today , Deputy Managing Editor , Secondary Malignant Neoplastic Disease , Disorder Of Skin , Eruption Of Skin , Carcinoma Of Prostate , Malignant Tumor Of Prostate , வடக்கு கரோலினா , ஒன்றுபட்டது மாநிலங்களில் , டியூக் பல்கலைக்கழகம் , பிரிட்ஜெட் கூன்ட்ஸ் , நோயல் கிளார்க் , தாமஸ் நம்பிக்கை , ஈயந் இஂக்ரம் ,

Is This Really Cancer?


In prostate cancer, as in life, you roll the dice.
In craps, 3+3 is called a hard six. It s hard because you can only win if you repeat with a combination of 3+3. Any other sixes you roll 4+2, 5+1 are losers.
Gleason 3+3 is a hard six in prostate cancer. It is the lowest grade cancer in the traditional Gleason scoring system. Still, to the eye of a pathologist, a Gleason 6 looks like a malignancy.
Now, a few experts are questioning whether this hard six is a cancer at all. Some urologists see a Gleason 6 as a noncancerous growth that has the potential to be invasive, but most likely will never spread to other organs or end up killing a man. ....

United States , Scott Eggener , Laurence Klotz , Edward Uthman , Jonathan Epstein , Georged Lundberg , Bert Vorstman , Johns Hopkins , William Catalona , Peter Carroll , University Of Texas Mcgovern Medical School , University Of Chicago , International Society Of Urological Pathology , University Of California San Francisco , Grade Group , Texas Society Of Pathologists , Northwestern University , California San Francisco , International Society , Urological Pathology , Texas Society , Texas Mcgovern Medical School , Disorder Of Skin , Eruption Of Skin , Neoplastic Disease , Basal Cell Carcinoma ,