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IDP Pharma announces first patient dosed in a Phase 1/2 Clinical Trial of IDP-121, a direct cMyc protein inhibitor and degrader

IDP Pharma announces first patient dosed in a Phase 1/2 Clinical Trial of IDP-121, a direct cMyc protein inhibitor and degrader
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Castillay Leóp , Noord Holland , Comunidad Autonoma De Cataluna , Israel General , Laura Nevola , Arrixaca Murcia , Universitario Marqu , Enrique Ocio , Valentin Caba , Division Of Oncology , Stanford University , Lifespring Life Sciences Communication , Virgen De La Arrixaca , Professor Dean Felsher , Scientific Adviser , Santiago Esteban , Chief Executive Officer , Professor Enrique Ocio , Hospital Universitario Marqu , Hospital Vall , Hospital Universitario , Parc Cient , Chief Executive , Spring Life Sciences Communication ,

ASH: Melflufen Appears Effective When Combined with Other Agents

Dec 11, 2020
Daratumumab and bortezomib work well with novel conjugate
A high percentage of patients diagnosed with relapsed or refractory multiple myeloma who have been treated with previous lines of therapy responded to investigative aminopeptide conjugate melflufen in combination with dexamethasone and either daratumumab (Darzalex) or bortezomib (Velcade), researchers found.
Among 13 patients treated with melflufen (melphalan flufenamide), bortezomib, and dexamethasone, the overall response rate was 62% (8 patients) four of those eight patients achieved a very good partial response or better, and one achieved a complete response in the ANCHOR trial, reported Enrique Ocio, MD, PhD, head of the department of hematology at University Hospital Marqués de Valdecilla, University of Cantabria, Santander, Spain. ....

New York , United States , Lake Success , Enrique Ocio , Wasif Saif , Pedward Susman , American Society Of Hematology , Northwell Health Cancer Institute , University Hospital Marqu , University Of Cantabria , American Society , Contributing Writer , புதியது யார்க் , ஒன்றுபட்டது மாநிலங்களில் , ஏரி வெற்றி , வாசிப் சைஃப் , எட்வர்ட் சுஸ்மான் , அமெரிக்கன் சமூகம் ஆஃப் ஹீமாட்டாலஜி , நார்த்வெல் ஆரோக்கியம் புற்றுநோய் நிறுவனம் , பல்கலைக்கழகம் ஆஃப் கான்டாப்ரியா , அமெரிக்கன் சமூகம் ,