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ELAINE-3 Trial Sets Out to Confirm Clinical Benefit of Lasofoxifene/Abemaciclib in ESR1+-Mutant, ER+ Breast Cancer

Seth A. Wander, MD, PhD, discusses key findings with lasofoxifene from ELAINE-1 and ELAINE-2 that supported the initiation of the ELAINE-3 trial. ....

United States , Harvard Medical School , Massachusetts General Hospital , Esr1 Er Her2 Metastatic Breast Cancer , Elaine 3 , Elaine 1 , Elaine 2 ,

Dr Jhaveri on the Rationale for the ELAINE-3 Trial in ESR1-Mutant ER+/HER2– Breast Cancer

Komal Jhaveri, MD, FACP, discusses the rationale for investigating lasofoxifene alongside abemaciclib in ESR1-mutated estrogen receptor–positive, HER2-negative metastatic breast cancer. ....

James Cayne , Komal Jhaveri , Memorial Sloan Kettering Cancer Center , Early Drug Development Service , Endocrine Therapy Research Program , James Cayne Chair , Junior Faculty , Elaine 3 , Elaine 1 , Elaine 2 , Esr1 Mutant , Er Her2 Negative Breast Cancer ,