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New 3M Harvest RC clarifier brings chromatography technology to harvest clarification with a single-stage solution for upstream processes

(0) ST. PAUL, Minn., June 1, 2021 /PRNewswire/ 3M Health Care launched 3M Harvest RC clarifier, leveraging its proprietary fibrous chromatography media to deliver a single-stage purification solution for recombinant protein therapeutic manufacturing. It is the next generation in harvest and clarification technology and is designed as an efficient option to increase monoclonal antibody (mAb) yields while streamlining a traditionally multi-stage harvest clarification process into a single stage. As cell culture processes are intensified to yield higher cell densities and product titers, the ability to effectively harvest the cell culture fluid with the consistency and scalability required becomes challenging, said Dr. Alexei Voloshin, global application development manager, 3M Separation and Purification Sciences. The 3M Harvest RC clarifier is an innovative solution that combats these challenges while eliminating several steps to improve the biopharmaceutical purification proce

New 3M™ Harvest RC clarifier brings chromatography technology to harvest clarification with a single-stage solution for upstream processes

Share this article Share this article ST. PAUL, Minn., June 1, 2021 /PRNewswire/  3M Health Care launched 3M™ Harvest RC clarifier, leveraging its proprietary fibrous chromatography media to deliver a single-stage purification solution for recombinant protein therapeutic manufacturing. It is the next generation in harvest and clarification technology and is designed as an efficient option to increase monoclonal antibody (mAb) yields while streamlining a traditionally multi-stage harvest clarification process into a single stage. 3M™ Harvest RC clarifier introduces chromatography technology to the harvest process enabling single-stage clarification of high-density cell culture fluid resulting in robust soluble and insoluble contaminant separation and high product recovery.

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