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mRNA-4157 Plus Pembrolizumab Improves DMFS in High-Risk Melanoma

The combination of mRNA-4157 and pembrolizumab reduced the risk of developing distant metastasis or death by approximately 65% compared with pembrolizumab alone as adjuvant therapy in patients with resected melanoma at high risk of recurrence, according to findings from the phase 2 KEYNOTE-942 trial. ....

Muhammad Adnan Khattak , Edith Cowan University In Joondalup , Moderna Inc , Clinical Research , One Clinical Research , Edith Cowan University , Asco Annual Meeting , Rna 4157 V940 , Ct03897881 , Phase 2 Keynote 942 Trial ,