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Microbial production of natural rainbow colorants

 E-Mail IMAGE: Figure: Systems metabolic engineering was employed to construct and optimize the metabolic pathways and membrane engineering was employed to increase the production of the target colorants, successfully producing the seven. view more  Credit: KAIST A research group at KAIST has engineered bacterial strains capable of producing three carotenoids and four violacein derivatives, completing the seven colors in the rainbow spectrum. The research team integrated systems metabolic engineering and membrane engineering strategies for the production of seven natural rainbow colorants in engineered Escherichia coli strains. The strategies will be also useful for the efficient production of other industrially important natural products used in the food, pharmaceutical, and cosmetic industries.

Newly Engineered Bacterium can Produce Carminic Acid

Newly Engineered Bacterium can Produce Carminic Acid Written by AZoMApr 7 2021 A team of researchers from the Korea Advanced Institute of Science and Technology (KAIST) has designed a bacterium that can produce carminic acid a natural red colorant that is extensively used in cosmetics and food. A schematic biosynthetic pathway for the production of carminic acid from glucose. Biochemical reaction analysis and computer simulation-assisted enzyme engineering were employed to identify and improve the enzymes (DnrFP217K and GtCGTV93Q/Y193F) responsible for the latter two reactions. Image Credit: The Korea Advanced Institute of Science and Technology (KAIST). The researchers have demonstrated the entire biosynthesis of carminic acid from glucose in a newly designed

Microbial production of a natural red colorant carminic acid

 E-Mail IMAGE: Figure: A schematic biosynthetic pathway for the production of carminic acid from glucose. Biochemical reaction analysis and computer simulation-assisted enzyme engineering was employed to identify and improve the enzymes (DnrFP217K. view more  Credit: KAIST A research group at KAIST has engineered a bacterium capable of producing a natural red colorant, carminic acid, which is widely used for food and cosmetics. The research team reported the complete biosynthesis of carminic acid from glucose in engineered Escherichia coli. The strategies will be useful for the design and construction of biosynthetic pathways involving unknown enzymes and consequently the production of diverse industrially important natural products for the food, pharmaceutical, and cosmetic industries.

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