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Repurposed drugs present new strategy for treating COVID-19: Study
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Repurposed drugs present new strategy for treating COVID-19
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Microbial Production Of A Natural Red Colorant Carminic Acid
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Newly Engineered Bacterium can Produce Carminic Acid
Written by AZoMApr 7 2021
A team of researchers from the Korea Advanced Institute of Science and Technology (KAIST) has designed a bacterium that can produce carminic acid a natural red colorant that is extensively used in cosmetics and food.
A schematic biosynthetic pathway for the production of carminic acid from glucose. Biochemical reaction analysis and computer simulation-assisted enzyme engineering were employed to identify and improve the enzymes (DnrFP217K and GtCGTV93Q/Y193F) responsible for the latter two reactions. Image Credit: The Korea Advanced Institute of Science and Technology (KAIST).
The researchers have demonstrated the entire biosynthesis of carminic acid from glucose in a newly designed
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IMAGE: Figure: A schematic biosynthetic pathway for the production of carminic acid from glucose. Biochemical reaction analysis and computer simulation-assisted enzyme engineering was employed to identify and improve the enzymes (DnrFP217K. view more
Credit: KAIST
A research group at KAIST has engineered a bacterium capable of producing a natural red colorant, carminic acid, which is widely used for food and cosmetics. The research team reported the complete biosynthesis of carminic acid from glucose in engineered Escherichia coli. The strategies will be useful for the design and construction of biosynthetic pathways involving unknown enzymes and consequently the production of diverse industrially important natural products for the food, pharmaceutical, and cosmetic industries.