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Just a bit of bad eating breeds bad gut bacteria – Times News Online

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United States , Karen Madsen , University Of Alberta , Department Of Medicine Division Gastroenterology , Medicine Division , Scientific Reports , Dietary Guidelines , ஒன்றுபட்டது மாநிலங்களில் , கரேன் பைத்தியம் , பல்கலைக்கழகம் ஆஃப் ஆல்பர்ட்டா , துறை ஆஃப் மருந்து பிரிவு இரைப்பை குடல் , மருந்து பிரிவு , அறிவியல் அறிக்கைகள் , உணவு வழிகாட்டுதல்கள் ,

Study describes IgG antibodies in Crohn's disease specific for human bacterial flagellins

Study describes IgG antibodies in Crohn s disease specific for human bacterial flagellins
Last year, Charles O. Elson, M.D., demonstrated a potential preventive treatment for Crohn s disease, a form of inflammatory bowel disease. He used a mouse model that included immune-reactive T cells from patients with Crohn s disease in a flagellin peptide-specific immunotherapy.
This study provided proof-of-principle that a flagellin-directed immunotherapy might provide similar benefits in patients.
Now University of Alabama at Birmingham researchers have moved a step closer to possible clinical testing of this treatment, say Elson and co-first authors Katie Alexander, Ph.D., and Qing Zhao, M.D., Ph.D. Their study, published in the journal ....

Charleso Elson , Qing Zhao , Katie Alexander , Emily Henderson , Department Of Medicine Division Gastroenterology , University Of Alabama At Birmingham , Medicine Division , குயிங் ழோ , கேடீ அலெக்சாண்டர் , எமிலி ஹென்டர்சன் , துறை ஆஃப் மருந்து பிரிவு இரைப்பை குடல் , பல்கலைக்கழகம் ஆஃப் அலபாமா இல் பர்மிங்காம் , மருந்து பிரிவு ,

Crohn's disease patients have specific IgG antibodies to human bacterial flagellins

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IMAGE: Last year, researchers used a mouse model that included immune-reactive T cells from patients with Crohn s disease in a proof-of-principle demonstration that a flagellin-directed immunotherapy might provide similar benefits in.
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Credit: UAB
BIRMINGHAM, Ala. - Last year, Charles O. Elson, M.D., demonstrated a potential preventive treatment for Crohn s disease, a form of inflammatory bowel disease. He used a mouse model that included immune-reactive T cells from patients with Crohn s disease in a flagellin peptide-specific immunotherapy. This study provided proof-of-principle that a flagellin-directed immunotherapy might provide similar benefits in patients.
Now University of Alabama at Birmingham researchers have moved a step closer to possible clinical testing of this treatment, say Elson and co-first authors Katie Alexander, Ph.D., and Qing Zhao, M.D., Ph.D. Their study, published in the journal ....

United States , Peterj Mannon , Charleso Elson , Qing Zhao , Katie Alexander , Basili Hirschowitz , Alexanderf Rosenberg , Meagan Reif , National Institutes Of Health , Department Of Medicine Division Gastroenterology , University Of Alabama At Birmingham , Department Of Microbiology , Colitis Foundation Of America , Department Of Veterans Affairs , Department Of Medicine , Rainin Foundation , Medicine Division , Lennard Wayne Duck , Colitis Foundation , Veterans Affairs , National Institutes , Synergy Award , Endowed Chair , Medicine Health , Immunology Allergies Asthma , Internal Medicine ,