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Novartis presents pivotal Phase III APPLY-PNH data at ASH demonstrating investigational oral monotherapy iptacopan superiority over anti-C5

Novartis presents pivotal Phase III APPLY-PNH data at ASH demonstrating investigational oral monotherapy iptacopan superiority over anti-C5
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Novartis Experimental Therapy Bests C5 Inhibitors in Phase 3 PNH Study

Novartis Experimental Therapy Bests C5 Inhibitors in Phase 3 PNH Study
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David Soergel , Drug Administration Breakthrough Therapy Designation , European Medicines Agency ,

Novartis: Phase III APPOINT-PNH Study Of Oral Monotherapy Iptacopan Meets Primary Endpoint

BASEL (dpa-AFX) - Swiss drug maker Novartis AG (NVS) announced Thursday that Phase III APPOINT-PNH study (NCT04820530) of investigational oral monotherapy iptacopan in complement-inhibitor-naïve ....

David Soergel , Metabolism Development Unit , More Such Health News , Global Head ,

Novartis investigational iptacopan provides clinically meaningful increases in hemoglobin levels in complement-inhibitor-naïve patients with PNH

Phase III APPOINT-PNH study of investigational oral monotherapy iptacopan met its primary endpoint; second positive Phase III topline readout for iptacopan in. ....

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Novartis Pharma AG: New long-term Leqvio (inclisiran) data from Novartis show sustained efficacy and safety over four years

Results from ORION-3 open-label trial show twice-yearly Leqvio(inclisiran), as a complement to statin therapy, provides effective and sustained reductions in low-density lipoprotein cholesterol (LDL-C) ....

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