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Alzheimer's drug with modest benefits wins backing of FDA advisers

Donanemab slows progression of symptoms, but questions linger about the durability of its effect. Donanemab slows progression of symptoms, but questions linger about the durability of its effect. ....

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What middle-aged people can do now to help prevent dementia later

Intervening earlier to improve brain health might help you stay sharper as you age. ....

United States , Sebastian Dohm Hansen , David Knopman , Kristine Beate Walhovd , Terrie Moffitt , Ahmad Hariri , Las Vegas , Jessica Caldwell , Cleveland Clinic Women Alzheimer Movement Prevention Center , University Of Oslo , University College Cork , Duke University , Alzheimer Association , Cleveland Clinic , Movement Prevention Center , Mayo Clinic , Lifespan Changes , Preventing Dementia , Middle Age , Lifestyle Choices ,

Who Should—and Can—Get Lecanemab, the New Alzheimer Disease Drug? | Dementia and Cognitive Impairment | JAMA

This Medical News story examines the complexity of determining who to treat with lecanemab, the new Alzheimer disease drug. ....

United Kingdom , United States , New York , George Perry , Donna Wilcock , Eli Lilly , Russell Swerdlow , James Burke , Sam Grandy , Madhav Thambisetty , Alzeca Bioscience , Robert Howard , Libby Holman , Ivan Cheung , Xavier Becerra , David Knopman , Allison Parks , Bioenergetically Active Esters For Health , Recuerdo Pharmaceuticals , Cure Alzheimer Fund , Alzheimer Network For Treatment , Us Department Of Health , York Stem Cell Foundation , University Of Texas At San Antonio , Translational Neuroscience Section Laboratory Of Behavioral , Centers For Medicare Medicaid Services ,

For older adults at risk of cognitive decline, hearing aids may reduce risk by half

Hearing aids may improve the quality of life for people overall, but for older adults at risk of cognitive issues, using hearing aids for three years cut their rates of cognitive decline in half. ....

David Knopman , Alzheimer Association International Conference , Cognitive Health Evaluation In Elders , Cognitive Health Evaluation , Association International Conference , Mayo Clinic , Atherosclerosis Risk ,

Major US health systems expect to offer Alzheimer's drug Leqembi in a few months

Five major U.S. health systems said they would offer Eisai and Biogen's promising new Alzheimer's drug Leqembi after working out payment and administrative policies, and how to assess and monitor patients, most likely in the next month or two. Leqembi, which won full U.S. regulatory approval last month, is the first treatment proven to slow progression of the mind-robbing disease for people in the earliest stages of Alzheimer's. The disease affects an estimated 6.5 million people, most of whom are part of the U.S. government’s Medicare plan for people 65 and older. ....

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