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Arrowhead Pharmaceuticals Presents New Phase 2 Data of Plozasiran in Patients with Mixed Hyperlipidemia

- Plozasiran significantly lowered triglyceride levels with commensurate reductions in APOC3, non-HDL-C, and remnant cholesterol

- Data presented at European Atherosclerosis Society 92nd Congress. ....

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Promising Hyperlipidemia Treatment Lowers Cardiovascular Risk

Promising Hyperlipidemia Treatment Lowers Cardiovascular Risk
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Daniel Gaudet, MD, PhD: Contextualizing Plozasiran Data from SHASTA-2, Upcoming MUIR Data

Daniel Gaudet, MD, PhD, discusses SHASTA-2 data and what cardiologists could learn from the forthcoming 48-week MUIR trial data from EAS 2024. ....

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Triglyceride-Lowering Therapies Provide Favorable Outcomes in Early Testing

In Bridge-TIMI 73a and SHASTA-2, the RNA-silencing therapies cut triglycerides quickly, offering hope for hard-to-treat patients. ....

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Substantial Triglyceride Reduction With Plozasiran

In patients with severe hypertriglyceridemia who are at risk for acute pancreatitis, the drug brought about triglyceride reductions of more than 50% in the phase 2 SHASTA-2 study. ....

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