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How to kill the 'zombie' cells that make you age

How to kill the 'zombie' cells that make you age
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United States , South San Francisco , North Carolina , New York , Winston Salem , San Francisco , Mayo Clinic In Rochester , Memorial Sloan Kettering Cancer Center , Robin Mansukhani , Anirvan Ghosh , Paul Moorhead , Leonard Hayflick , Sundeep Khosla , Matthew Scholz , Scripps Research Institute In Jupiter , Corina Amor At Cold Spring Harbor Laboratory , Cellular Senescence Network Sennet , Mayo Clinic , Scripps Research Institute , Unity Biotechnology , Miranda Orr , Wake Forest University School , Corina Amor , Cold Spring Harbor Laboratory , Memorial Sloan Kettering Cancer , Deciduous Therapeutics ,

CAR T cells could slow aging by eliminating senescent cells

CAR T cells could be repurposed to target senescent cells and delay the effect of aging. A study by scientists at Cold Spring Harbor Laboratory showed how to design them and demonstrated the advantages of this therapy in mice. “We only gave one dose, and we could have benefits [for] really long periods of time,” lead author Corina Amor told BioWorld. ....

Corina Amor , Cold Spring Harbor Laboratory , Bioworld Science , Senescent Cells , Drug Design , Rug Delivery And Technologies , Car T ,

Senolytics to Tackle Age-Related Pathologies

The world is rapidly aging. According to the World Health Organization, 12% of the world population was aged 60 and above in 2015 and by 2050, that number will rise to 22%. Along with this demographic shift, there is an increase in the prevalence of age-related chronic diseases including cancer, liver fibrosis, and Alzheimer’s disease in which senescent cells have been implicated. ....

Corina Amor , University Of Leicester , Cold Spring Harbor Laboratory , Salvador Macip ,