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Discovery of widespread DNA damage in stem cell lines spurs call for pre-use sequencing

More than 70% of stem cell lines derived from human skin cells have damage to their DNA that could compromise their use in research and cell-based therapies. ....

United Kingdom , Foad Rouhani , Nick Paul Taylor , University Of Cambridge , Wellcome Sanger Institute , Science Advisory Board , Nature Genetics , Stem Cells , Dna Damage , Cell Therapy , Cell Therapies , Cell Based Therapies , Human Induced Pluripotent Stem Cells , Ucleotide Resolution Characterization , Genome Sequencing , Cor Mutations , Whole Genome Sequencing , Stem Cell Lines , Induced Pluripotent Stem Cells ,