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Human iPSCs restore muscle, function in monkeys with heart failure

Japanese researchers have transplanted human induced pluripotent stem cells (iPSCs) in a primate model of myocardial infarction and were able to restore heart muscle and function in monkeys. Developed by Tokyo-based Heartseed Inc., the grafted iPSCs consist of clusters of purified heart muscle cells (cardiomyocyte spheroids) that are injected into the myocardial layer of the heart. Published in Circulation on April 26, 2024, the study showed that the cardiomyocyte spheroids survived long term and showed improved contractile function with low occurrence of post-transplant arrhythmias.

Heartseed incTokyo based heartseed incBioworld scienceHeartseed incInduced pluripotent stem cellsHeart failureDrug designRug delivery and technologiesStem cells

Epigenomic analysis sheds light on risk factors for ALS

In a study of cells from nearly 400 amyotrophic lateral sclerosis (ALS) patients, MIT researchers identified genomic regions with chemical modifications linked to disease progression.

United statesLyle ostrowErnest fraenkelStanislav tsitkovAbbvie foundationBruce edwards foundationNational institutes of healthGroverm hermann professor in health sciencesNature communicationsBari lipp foundationCaterpillar foundationTeam gleasonRobert packard centerNational football leagueMuscular dystrophy associationA cure foundation

Global Induced Pluripotent Stem Cell (iPSC) Industry

Dublin, April 29, 2024 (GLOBE NEWSWIRE) The

United statesUnited kingdomHera biolabsAxol bioscienceNevia bioMasayo takahashiJames thomsonTakara bioShinya yamanakaAsia pacificExacis biotherapeuticsNeukio biotherapeuticsCellgenix gmbDrug developmentCentury therapeutics incCynata therapeutics ltd

Exploring New Horizons: BCC Research Forecasts $5 2 Billion Global Induced Pluripotent Stem Cells Market by 2028

/PRNewswire/ "According to the latest research study, the demand for Induced Pluripotent Stem Cells: Global Markets expected to grow from $3.4 billion in.

United statesMerck kgaaPluripotent stem cellsGlobal marketsInduced pluripotent stem cellsWorldwide induced pluripotent stem cellsMarket driversBiotechnology industryChronic diseasesSample copyReprogramming methodDerived tissue cell typeProduct functionEnd useKey market players areStem cells

Research and Markets: Induced Pluripotent Stem Cells Market Report, Featuring Historical Revenue Data for 2021 and 2022, Estimated Figures for 2023, and Compound Annual Growth Rates (CAGRs) through 2028

Research and Markets: Induced Pluripotent Stem Cells Market Report, Featuring Historical Revenue Data for 2021 and 2022, Estimated Figures for 2023, and Compound Annual Growth Rates (CAGRs) through 2028
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Laura woodStefan klotterWaisman biomanufacturingPluripotent stem cells research application marketAxol bioscience ltdCell signaling technologyBio techne corpPluripotent stem cells research product typesPluripotent stem cell contract service typesBristol myers squibbVertex pharmaceuticalsAcademic researchCompany profilesCorning incOffice hours callLonza group