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Muvalaplin, an Oral Small Molecule Inhibitor of Lipoprotein(a) Formation: A Randomized Clinical Trial | Cardiology | JAMA

This phase 1 randomized clinical trial evaluates the safety, tolerability, pharmacokinetics, and exploratory pharmacodynamic biomarker effects of muvalaplin in ....

United States , Noord Holland , South Australia , Eteläuomen Läi , Loredana Spoerri , Eli Lilly , Stephenj Nicholls , Esperion Therapeutics Inc , Pharma Group , Boehringer Ingelheim , Amsterdam Pharmaceuticals , Bristol Myers Squibb , Monash University , Victorian Heart Institute , Medicines Company , European Society Of Cardiology Congress , Alaska Native , Good Clinical , Siemens Healthcare Diagnostics , Pharmacodynamic Measurements , United Kingdom Biobank , Copenhagen General Population Study , Drs Nicholls , Interest Disclosures , New Amsterdam Pharma , New Amsterdam Pharmaceuticals ,

The World's First Drug to Treat Untreatable 'Bad Cholesterol': Study

The World's First Drug to Treat Untreatable 'Bad Cholesterol': Study
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United States , South Australia , Stephen Nicholls , Journal Of The American Medical Association , Drug Administration , Monash University , American Medical Association , Times Photo , Epoch Times , Copenhagen General Population Study , High Lipoprotein , James Dinicolantonio , Saint Luke , Mid America Heart Institute ,

Triglyceride Puzzle: Do TG Metabolites Better Predict Risk?

The findings are completely novel and may make people think differently about triglycerides and CV risk, said a researcher based on a preliminary study. ....

University Of Pennsylvania , United States , Michael Miller , World Health Organization , Hospital Of The University Pennsylvania , Corporal Michaelj Crescenz Va Medical Center , University Of Copenhagen , Copenhagen General Population Study , European Heart , Corporal Michaelj Crescenz , Ipid Management , Cardiometabolic Risk , Body Mass Index Bmi , Iological Marker , Biologic Therapy , Chronic Obstructive Pulmonary Disease Copd , Chronic Obstructive Pulmonary Disease , Chronic Obstructive Lung Disease ,

Subclinical coronary atherosclerosis tied to more than 8-fold increase in MI risk

Denmark: In middle-aged, asymptomatic adults, subclinical, obstructive coronary atherosclerosis is linked with a more than 8-fold increased risk for myocardial infarction over three years than those. ....

City Of , United Kingdom , Andreas Fuchs , Michael Mcdermott , Davide Newby , University Of Edinburgh , Copenhagen University Hospital , Copenhagen General Population Study , Coronary Atherosclerosis , Myocardial Infarction , Danish Cohort , Prospective Observational Cohort , Annals Of Internal Medicine , Schemic Heart Disease , Coronary Atherosclerosis , Myocardial Infarction , Coronary Artery Disease , Coronary Computed Tomography Angiography ,

Subclinical CAD by CT, Stenoses or Not, Predicts MI Risk

Even without symptoms, more atherosclerosis by CT angiography means greater MI risk, which climbs even further if there are obstructive lesions. ....

United Kingdom , City Of , United States , Andreas Fuchs , Ron Blankstein , Davide Newby , Michael Mcdermott , Centre For Cardiovascular Science , University Of Edinburgh , Copenhagen University Hospital , Copenhagen General Population Study , Copenhagen University Hospital Rigshospitalet , Screening Role , Cardiovascular Science , Computed Tomography Coronary Angiography , Primary Prevention , Myocardial Infarction , Cardiovascular Imaging , Ardiac Imaging , V Imaging , Acute Coronary Syndrome Acs , Cute Coronary Syndrome , Risk Factors For Coronary Artery Disease , Isk Factors For Coronary Heart Disease , Isk Factors For Atherosclerotic Heart Disease , Isk Factors For Atherosclerotic Cardiovascular Disease ,