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Artificial Intelligence Can Evaluate Cardiovascular Risk During CT Scan

Using two primary markers‑ coronary calcium and heart chamber size A routine chest scan without contrast shows promise for disease detection ....

Sumeet Chugh , Piotrj Slomka , Andrewj Einstein , Mark Lemley , Robert Jh Miller , Aakash Shanbhag , Annam Michalowska , Daniels Berman , Joannax Liang , Paulb Kavanagh , Cathleen Huang , Davide Newby , Konrad Pieszko , Damini Dey , Bryan Bednarski , Serged Van Kriekinge , Aditya Killekar , Smidt Heart Institute At Cedars , Department Of Cardiology , National Cancer Institute , Biomedical Imaging Research Institute , National Heart , Blood Institute National Institutes Of Health , National Institute Of Biomedical Imaging , National Institutes Of Health , Division Of Artificial Intelligence In Medicine ,

Implementation of a high sensitivity cardiac troponin I assay and risk of myocardial infarction or death at five years: observational analysis of a stepped wedge, cluster randomised controlled trial

Objective To evaluate the impact of implementing a high sensitivity assay for cardiac troponin I on long term outcomes in patients with suspected acute coronary syndrome.

Design Secondary observational analysis of a stepped wedge, cluster randomised controlled trial.

Setting 10 secondary and tertiary care centres in Scotland, UK.

Participants 48 282 consecutive patients with suspected acute coronary syndrome. Myocardial injury was defined as any high sensitivity assay result for cardiac troponin I >99th centile of 16 ng/L in women and 34 ng/L in men.

Intervention Hospital sites were randomly allocated to either early (n=5 hospitals) or late (n=5 hospitals) implementation of a high sensitivity cardiac troponin I assay with sex specific diagnostic thresholds.

Main outcome measure The main outcome was myocardial infarction or death at five years.

Results 10 360 patients had cardiac troponin concentrations greater than the 99th centile, of w ....

United Kingdom , City Of , Glasgow City , Davida Mcallister , Imran Sadat , Frank Finlay , Siemens Healthineers , Jasper Boeddinghaus , Michael Mcdermott , Heather Charles , Jack Pm Andrews , Jonathan Malo , Caelan Taggart , Dallan Walker , Richarda Parker , Donogh Maguire , Andrewr Chapman , Alastair Moss , Colin Berry , Stephanie Barker , Catriona Keerie , John Hung , Colinm Fischbacher , Shannon Amoils , Chris Tuck , Stephen Young ,

Subclinical coronary atherosclerosis tied to more than 8-fold increase in MI risk

Denmark: In middle-aged, asymptomatic adults, subclinical, obstructive coronary atherosclerosis is linked with a more than 8-fold increased risk for myocardial infarction over three years than those. ....

City Of , United Kingdom , Andreas Fuchs , Michael Mcdermott , Davide Newby , University Of Edinburgh , Copenhagen University Hospital , Copenhagen General Population Study , Coronary Atherosclerosis , Myocardial Infarction , Danish Cohort , Prospective Observational Cohort , Annals Of Internal Medicine , Schemic Heart Disease , Coronary Atherosclerosis , Myocardial Infarction , Coronary Artery Disease , Coronary Computed Tomography Angiography ,

Subclinical CAD by CT, Stenoses or Not, Predicts MI Risk

Even without symptoms, more atherosclerosis by CT angiography means greater MI risk, which climbs even further if there are obstructive lesions. ....

United Kingdom , City Of , United States , Andreas Fuchs , Ron Blankstein , Davide Newby , Michael Mcdermott , Centre For Cardiovascular Science , University Of Edinburgh , Copenhagen University Hospital , Copenhagen General Population Study , Copenhagen University Hospital Rigshospitalet , Screening Role , Cardiovascular Science , Computed Tomography Coronary Angiography , Primary Prevention , Myocardial Infarction , Cardiovascular Imaging , Ardiac Imaging , V Imaging , Acute Coronary Syndrome Acs , Cute Coronary Syndrome , Risk Factors For Coronary Artery Disease , Isk Factors For Coronary Heart Disease , Isk Factors For Atherosclerotic Heart Disease , Isk Factors For Atherosclerotic Cardiovascular Disease ,

Subclinical, Asymptomatic Atherosclerosis Linked to 8-Fold Increase in Myocardial Infarction

An analysis of more than 9000 adults aged 40 and older without known cardiovascular disease is shedding new light on the risk of myocardial infarction and mortality associated with subclinical coronary atherosclerosis. ....

City Of , United Kingdom , Rigshospitalet Klaus Fuglsang Kofoed , Michael Mcdermott , Davide Newby , British Heart Foundation Centre For Cardiovascular Science , University Of Copenhagen , University Of Edinburgh , Klaus Fuglsang Kofoed , Copenhagen General Population Study , British Heart Foundation Centre , Cardiovascular Science ,