Community Health Index Advisory Group News Today : Breaking News, Live Updates & Top Stories | Vimarsana

Stay updated with breaking news from Community health index advisory group. Get real-time updates on events, politics, business, and more. Visit us for reliable news and exclusive interviews.

Top News In Community Health Index Advisory Group Today - Breaking & Trending Today

l-carnitine, a friend or foe for cardiovascular disease? A Mendelian randomization study | BMC Medicine

L-carnitine is emerging as an item of interest for cardiovascular disease (CVD) prevention and treatment, but controversy exists. To examine the effectiveness and safety of l-carnitine, we assessed how genetically different levels of l-carnitine are associated with CVD risk and its risk factors. Given higher CVD incidence and l-carnitine in men, we also examined sex-specific associations. We used Mendelian randomization to obtain unconfounded estimates. Specifically, we used genetic variants to predict l-carnitine, and obtained their associations with coronary artery disease (CAD), ischemic stroke, heart failure, and atrial fibrillation, as well as CVD risk factors (type 2 diabetes, glucose, HbA1c, insulin, lipid profile, blood pressure and body mass index) in large consortia and established cohorts, as well as sex-specific association in the UK Biobank. We obtained the Wald estimates (genetic association with CVD and its risk factors divided by the genetic association with l-carnitine ....

Eteläuomen Läi , United Kingdom , Finngen Biobank , Research Ethics Committee , Global Lipids Genetics Consortium , Patient Information Advisory Group , Neale Lab , Saf Consortium , Community Health Index Advisory Group , R Foundation For Statistical Computing , United Kingdom Biobank , Heart Failure Molecular Epidemiology , Therapeutic Targets , United Kingdom Biobank Axiom , Genetic Investigation , Statistical Computing , United Kingdom Biobank Resource , North West Multi Centre Research Ethics Committee ,

Accelerometer measured physical activity and the incidence of cardiovascular disease: Evidence from the UK Biobank cohort study


Research Article
Accelerometer measured physical activity and the incidence of cardiovascular disease: Evidence from the UK Biobank cohort study
Rema Ramakrishnan,
Roles
Data curation,
Formal analysis,
Investigation,
Methodology,
Software,
Validation,
Writing – original draft,
Writing – review & editing
Affiliations
Nuffield Department of Women’s and Reproductive Health, University of Oxford, Oxford, United Kingdom,
University of New South Wales, Sydney, Australia
Roles
Investigation,
Methodology,
Resources,
Validation,
Writing – review & editing
Affiliations
Big Data Institute, Li Ka Shing Centre for Health Information and Discovery, University of Oxford, Oxford, United Kingdom,
Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom,
National Institute of Health Re ....

United Kingdom , United States , Amanda Paluch , International Classification Of Diseases , University Of Massachusetts Amherst , Oxford Martin School , Global Challenge Research Fund Grant Ref , Community Health Index Advisory Group , British Heart Foundation , Oxford Biomedical Research Centre , Department Of Health , Research Council , Oxford Biomedical Research Computing , Alan Turing Institute , National Institute Of Health Research , University Of Oxford , United Kingdom Research , National Information Governance Board For Health , Multicentre Research Ethics Committee , National Institute For Health Research , Big Data Institute , Health Data Research United Kingdom , Wellcome Centre For Human Genetics , Research Council Industrial Strategy Studentship , United Kingdom Biobank , Kingdom Biobank ,