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Ultra-processed food consumption, cancer risk and cancer mortality: a large-scale prospective analysis within the UK Biobank

Our UK-based cohort study suggests that higher UPF consumption may be linked to an increased burden and mortality for overall and certain site-specific cancers especially ovarian cancer in women.

United-kingdom
Scotland
Oxford-web
Research-ethics-committee
International-agency-for-research-on-cancer
Public-health-nutr
United-kingdom-biobank
Oxford-webq
Health-nutr
North-west-multi-centre-research-ethics-committee
International-agency

Healthy lifestyle behaviors, mediating biomarkers, and risk of microvascular complications among individuals with type 2 diabetes: A cohort study

Tingting Geng and colleagues investigate whether lifestyle behaviours could affect microvascular complications among patients with type 2 diabetes in the UK Biobank.

China
Hubei
Guangdong
Shanghai
United-states
United-kingdom
Da-qing
Sichuan
Scotland
American
Weiping-jia
National-nature-science-foundation-of-china

l-carnitine, a friend or foe for cardiovascular disease? A Mendelian randomization study | BMC Medicine

l-carnitine is emerging as an item of interest for cardiovascular disease (CVD) prevention and treatment, but controversy exists. To examine the effectiveness and safety of l-carnitine, we assessed how genetically different levels of l-carnitine are associated with CVD risk and its risk factors. Given higher CVD incidence and l-carnitine in men, we also examined sex-specific associations. We used Mendelian randomization to obtain unconfounded estimates. Specifically, we used genetic variants to predict l-carnitine, and obtained their associations with coronary artery disease (CAD), ischemic stroke, heart failure, and atrial fibrillation, as well as CVD risk factors (type 2 diabetes, glucose, HbA1c, insulin, lipid profile, blood pressure and body mass index) in large consortia and established cohorts, as well as sex-specific association in the UK Biobank. We obtained the Wald estimates (genetic association with CVD and its risk factors divided by the genetic association with l-carnitine

Helsinki
Eteläuomen-läi
Finland
Austria
Vienna
Wien
United-kingdom
Scotland
British
Finngen-biobank
Research-ethics-committee
Global-lipids-genetics-consortium

Brain imaging before and after COVID-19 in UK Biobank

Brain imaging before and after COVID-19 in UK Biobank
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Research-ethics-committee
Wellcome-centre-for-integrative-neuroimaging
Wellcome-trust-senior-research-fellowship
Wellcome-trust-collaborative-award
Wellcome
Kingdom-biobank
United-kingdom-biobank
Wellcome-centre
Integrative-neuroimaging
Wellcome-trust
United-kingdom-biobank-resource
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