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CFTR modulator can be safe, well-tolerated for younger children with common form of cystic fibrosis


CFTR modulator can be safe, well-tolerated for younger children with common form of cystic fibrosis
Children ages two to five who have the most common form of cystic fibrosis (CF), caused by two copies of the F508 gene mutation, have not had any modulator treatments available to them until recently. A new study authored by researchers at Children s Hospital Colorado and published May 6, 2021, in
Lancet Respiratory Medicine shows that the CFTR modulator - lumacaftor/ivacaftor - can be safe and well-tolerated for this age range for up to 120 weeks, allowing younger children to begin proactive treatment of CF earlier in their lives. ....

United States , Ronald Sokol , Jordana Hoppe , Emily Henderson , Children Hospital Colorado Breathing Institute , Mike Mcmorris Cystic Fibrosis Research , Therapeutics Development Network , Care Center , University Of Colorado School Medicine , Translational Sciences Institute , Translational Research Center , Hospital Colorado , Lancet Respiratory Medicine , Colorado School , Anschutz Medical , Colorado Clinical , Hospital Colorado Breathing Institute , ஒன்றுபட்டது மாநிலங்களில் , ரொனால்ட் சொக்ொள் , ஜோர்டானா ஹாப் , எமிலி ஹென்டர்சன் , குழந்தைகள் மருத்துவமனை கொலராடோ சுவாசம் நிறுவனம் , மைக் மக்மொர்றிச் சிஸ்டிக் ஃபைப்ரோஸிஸ் ஆராய்ச்சி , சிகிச்சை வளர்ச்சி வலைப்பின்னல் , பராமரிப்பு மையம் , பல்கலைக்கழகம் ஆஃப் கொலராடோ பள்ளி மருந்து ,

New study determines cystic fibrosis therapy is safe and effective for young children


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IMAGE: Lead study author Jordana Hoppe, MD, a pediatric pulmonologist with Children s Hospital Colorado and assistant professor of pediatrics at the University of Colorado School of Medicine on the Anschutz Medical.
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Credit: Children s Hospital Colorado
Children ages two to five who have the most common form of cystic fibrosis (CF), caused by two copies of the F508 gene mutation, have not had any modulator treatments available to them until recently. A new study authored by researchers at Children s Hospital Colorado and published May 6, 2021, in
Lancet Respiratory Medicine shows that the CFTR modulator - lumacaftor/ivacaftor - can be safe and well-tolerated for this age range for up to 120 weeks, allowing younger children to begin proactive treatment of CF earlier in their lives. ....

United States , Ronald Sokol , Jordana Hoppe , Children Hospital Colorado Breathing Institute , Mike Mcmorris Cystic Fibrosis Research , Therapeutics Development Network , Care Center , University Of Colorado School Medicine , Translational Sciences Institute , Translational Research Center , Hospital Colorado , Lancet Respiratory Medicine , Colorado School , Anschutz Medical , Colorado Clinical , Hospital Colorado Breathing Institute , ஒன்றுபட்டது மாநிலங்களில் , ரொனால்ட் சொக்ொள் , ஜோர்டானா ஹாப் , குழந்தைகள் மருத்துவமனை கொலராடோ சுவாசம் நிறுவனம் , மைக் மக்மொர்றிச் சிஸ்டிக் ஃபைப்ரோஸிஸ் ஆராய்ச்சி , சிகிச்சை வளர்ச்சி வலைப்பின்னல் , பராமரிப்பு மையம் , பல்கலைக்கழகம் ஆஃப் கொலராடோ பள்ளி மருந்து , மொழிபெயர்ப்பு அறிவியல் நிறுவனம் , மொழிபெயர்ப்பு ஆராய்ச்சி மையம் ,

Researchers to test a promising treatment for high-risk COVID-19 outpatients


Researchers to test a promising treatment for high-risk COVID-19 outpatients
The nation has been coping with the pandemic for more than a year, and in this time, researchers have learned a great deal about how to treat COVID-19. Yet they have also been faced with what they still must learn, including how to reach the individuals who have been most dramatically impacted by the disease and who could benefit the most from new treatments.
A new $8.7 million grant from the National Institutes of Health (NIH) will fuel these efforts for the next two years. Adit Ginde, MD, MPH, professor of emergency medicine at CU School of Medicine and UCHealth emergency physician is leading a team of researchers from the Colorado Clinical and Translational Sciences Institute at the University of Colorado Anschutz Medical Campus to test the real-world effectiveness of a promising treatment for high-risk COVID-19 outpatients. ....

United States , Matthew Wynia , Bethany Kwan , Nichole Carlson , Eli Lilly , Emily Henderson , Cu School Of Medicine , Translational Sciences Institute , National Institutes Of Health , University Of Colorado Anschutz Medical Campus , National Institutes , Colorado Clinical , Colorado Anschutz Medical Campus , Emergency Medicine , Tell Bennett , Public Health , ஒன்றுபட்டது மாநிலங்களில் , பெத்தானி க்வ்யாந் , நிக்கோல் கார்ல்சன் , எலி லில்லி , எமிலி ஹென்டர்சன் , சு பள்ளி ஆஃப் மருந்து , மொழிபெயர்ப்பு அறிவியல் நிறுவனம் , தேசிய நிறுவனங்கள் ஆஃப் ஆரோக்கியம் , பல்கலைக்கழகம் ஆஃப் கொலராடோ அண்சச்சுட்ஸ் மருத்துவ வளாகம் , தேசிய நிறுவனங்கள் ,