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CFTR modulator can be safe, well-tolerated for younger children with common form of cystic fibrosis

CFTR modulator can be safe, well-tolerated for younger children with common form of cystic fibrosis
Children ages two to five who have the most common form of cystic fibrosis (CF), caused by two copies of the F508 gene mutation, have not had any modulator treatments available to them until recently. A new study authored by researchers at Children s Hospital Colorado and published May 6, 2021, in
Lancet Respiratory Medicine shows that the CFTR modulator - lumacaftor/ivacaftor - can be safe and well-tolerated for this age range for up to 120 weeks, allowing younger children to begin proactive treatment of CF earlier in their lives. ....

United States , Ronald Sokol , Jordana Hoppe , Emily Henderson , Children Hospital Colorado Breathing Institute , Mike Mcmorris Cystic Fibrosis Research , Therapeutics Development Network , Care Center , University Of Colorado School Medicine , Translational Sciences Institute , Translational Research Center , Hospital Colorado , Lancet Respiratory Medicine , Colorado School , Anschutz Medical , Colorado Clinical , Hospital Colorado Breathing Institute , ஒன்றுபட்டது மாநிலங்களில் , ரொனால்ட் சொக்ொள் , ஜோர்டானா ஹாப் , எமிலி ஹென்டர்சன் , குழந்தைகள் மருத்துவமனை கொலராடோ சுவாசம் நிறுவனம் , மைக் மக்மொர்றிச் சிஸ்டிக் ஃபைப்ரோஸிஸ் ஆராய்ச்சி , சிகிச்சை வளர்ச்சி வலைப்பின்னல் , பராமரிப்பு மையம் , பல்கலைக்கழகம் ஆஃப் கொலராடோ பள்ளி மருந்து ,

New study determines cystic fibrosis therapy is safe and effective for young children

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IMAGE: Lead study author Jordana Hoppe, MD, a pediatric pulmonologist with Children s Hospital Colorado and assistant professor of pediatrics at the University of Colorado School of Medicine on the Anschutz Medical.
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Credit: Children s Hospital Colorado
Children ages two to five who have the most common form of cystic fibrosis (CF), caused by two copies of the F508 gene mutation, have not had any modulator treatments available to them until recently. A new study authored by researchers at Children s Hospital Colorado and published May 6, 2021, in
Lancet Respiratory Medicine shows that the CFTR modulator - lumacaftor/ivacaftor - can be safe and well-tolerated for this age range for up to 120 weeks, allowing younger children to begin proactive treatment of CF earlier in their lives. ....

United States , Ronald Sokol , Jordana Hoppe , Children Hospital Colorado Breathing Institute , Mike Mcmorris Cystic Fibrosis Research , Therapeutics Development Network , Care Center , University Of Colorado School Medicine , Translational Sciences Institute , Translational Research Center , Hospital Colorado , Lancet Respiratory Medicine , Colorado School , Anschutz Medical , Colorado Clinical , Hospital Colorado Breathing Institute , ஒன்றுபட்டது மாநிலங்களில் , ரொனால்ட் சொக்ொள் , ஜோர்டானா ஹாப் , குழந்தைகள் மருத்துவமனை கொலராடோ சுவாசம் நிறுவனம் , மைக் மக்மொர்றிச் சிஸ்டிக் ஃபைப்ரோஸிஸ் ஆராய்ச்சி , சிகிச்சை வளர்ச்சி வலைப்பின்னல் , பராமரிப்பு மையம் , பல்கலைக்கழகம் ஆஃப் கொலராடோ பள்ளி மருந்து , மொழிபெயர்ப்பு அறிவியல் நிறுவனம் , மொழிபெயர்ப்பு ஆராய்ச்சி மையம் ,

Colorado school-based initiative aims to help disadvantaged kids with asthma breathe better

Colorado school-based initiative aims to help disadvantaged kids with asthma breathe better
The National Institute of Health s (NIH) National Heart, Lung and Blood Institute (NHLBI) is supporting an estimated 3-year, $2.7 million award to the University of Colorado Denver through its Disparities Elimination through Coordinated Interventions to Prevent and Control Heart and Lung Disease Risk (DECIPHeR) initiative to address health disparities in diverse Colorado communities. The overarching goal is to help disadvantaged kids with uncontrolled asthma breathe better.
The DECIPHeR Alliance is composed of seven research centers across the United States plus a research coordinating center. The Colorado DECIPHeR site is made up of team members from Children s Hospital Colorado s (Children s Colorado) Breathing Institute, National Jewish Health, University of Colorado School of Medicine (CUSOM), Colorado Comprehensive School-Centered Asthma Program (AsthmaCOMP), and the Adult and ....

United States , University Of Colorado Denver , National Jewish Health , Lisa Cicutto , Arthur Mcfarlane , Amy Huebschmann , Melanie Gleason , Stanley Szefler , Emily Henderson , Asthma Attacks In Disadvantaged School Children , Decipher Alliance , National Institute Of Health , Pediatric Asthma Research Program , Children Colorado Breathing Institute , Children Hospital Colorado Breathing Institute , Community Research At National Jewish Health , University Of Colorado School Medicine , Child Consortium For Health Outcomes Research , Blood Institute , Colorado Department Of Public Health , National Heart , Colorado Comprehensive School , Asthma Program , National Institute , Colorado Denver , Disparities Elimination ,

Colorado school-based asthma program to improve health equity for children

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Aurora, Colo. (Feb. 17, 2021) ? The National Institute of Health s (NIH) National Heart, Lung and Blood Institute (NHLBI) is supporting an estimated 3-year, $2.7 million award to the University of Colorado Denver through its Disparities Elimination through Coordinated Interventions to Prevent and Control Heart and Lung Disease Risk (DECIPHeR) initiative to address health disparities in diverse Colorado communities. The overarching goal is to help disadvantaged kids with uncontrolled asthma breathe better.
The DECIPHeR Alliance is composed of seven research centers across the United States plus a research coordinating center. The Colorado DECIPHeR site is made up of team members from Children s Hospital Colorado s (Children s Colorado) Breathing Institute, National Jewish Health, University of Colorado School of Medicine (CUSOM), Colorado Comprehensive School-Centered Asthma Program (AsthmaCOMP), and the Adult and Child Consortium for Health Outcomes Research and ....

United States , University Of Colorado Denver , National Jewish Health , Lisa Cicutto , Arthur Mcfarlane , Amy Huebschmann , Melanie Gleason , Stanley Szefler , Asthma Attacks In Disadvantaged School Children , Decipher Alliance , National Institute Of Health , Children Colorado Breathing Institute , Community Research At National Jewish Health , University Of Colorado School Medicine , Child Consortium For Health Outcomes Research , Blood Institute , Colorado Department Of Public Health , National Heart , Children Hospital Colorado Breathing Institute , Colorado Comprehensive School , Asthma Program , National Institute , Colorado Denver , Disparities Elimination , Coordinated Interventions , Control Heart ,