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Does the f. D. A. Encounter adverse events with o. T. C. Medicines . Dr. Woodcock i would say fairly frequently. To rise to a serious level, maybe once every several years. Mr. Butterfield frequently or infrequently . Dr. Woodcock fairly frequently. Given what they are and the exposure of the population to them but once perhaps every two years were facing an issue that we would like to get out rapidly to the public to notify them and our hands are really tied and we have to use this guidance process. Mr. Butterfield all right. Two other examples you highlighted in your written testimony related to pediatric issues with certain medicines. Would you say that a dispr portionate number of safety concerns with o. T. C. Medicines are related to pediatrics . Dr. Woodcock i would say in the last decade that is true, a decade or so, and the reason is starting in the late 1990s i think everyone became aware that you should study children and not just treat them as tiny adults and just scale down ....
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