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HUTCHMED Initiates Phase I Trial of Menin Inhibitor HMPL-506 in Patients with Hematological Malignancies in China

HUTCHMED Initiates Phase I Trial of Menin Inhibitor HMPL-506 in Patients with Hematological Malignancies in China
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Hong kongUnited kingdomAnn hematolJianxiang wangZhou yiShui weiBen atwell alex shawUnited kingdom medical research councilStock exchange of hong kongExchange commissionChina limitedNational cancer institutePhasei trialMenin inhibitorHematological malignanciesChinese academy

Implications for pathophysiology and therapeutics in chronic inflammatory disorder

This article explores the role of citrullination, a post-translational modification process, in the pathogenesis of chronic diseases such as rheumatoid arthritis, cancer, and neurodegenerative disorders

United statesSan diegoMaria osipovaSonoma biotherapeuticsSengenics corporationCancer researchSengenics corporation llcaprAmerican college of rheumatologyAmerican college of rheumatology convergenceAutoimmune autoantigen panelSponsored contentImage creditPan autoimmune autoantigen panelSoc open sciExp medClin invest

Dengue - The Lancet

Dengue - The Lancet
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Sri lankaUbon ratchathaniBasse normandieJapan generalRio de janeiroEstado do rioMaricopa countyUnited statesPan american health organizationDistrict of columbiaKrung thep mahanakhonRepublic ofFrance generalNew delhiKamphaeng phetHaute normandie

Individualised neoantigen therapy mRNA-4157 (V940) plus pembrolizumab versus pembrolizumab monotherapy in resected melanoma (KEYNOTE-942): a randomised, phase 2b study

Individualised neoantigen therapy mRNA-4157 (V940) plus pembrolizumab versus pembrolizumab monotherapy in resected melanoma (KEYNOTE-942): a randomised, phase 2b study
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Clin investClin oncolEnglj med

Using Amira Software to Measure 3D Organelle Morphology

This article from Thermo Fisher discusses a study published in 2022 where researchers used the Thermo Scientific™ Amira™ Software along with serial block-face scanning electron microscopy (SBF SEM). The result was that they were able to produce detailed 3D reconstructions of organelles.

Emily mageeAmira softwarePharmacological researchAmira software for cell biologySponsored contentThermo fisher scientificThermo scientificImage creditGenerating surfacesOrganelle morphology usingClin investReviews molecular cellDeep learningElectron microscopyHigh content screeningContent policy