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Why Americans lack adequate access to fertility treatments


Why Americans lack adequate access to fertility treatments
My husband and I are that one in eight.
When we decided to start our family in 2017, I was 29 years old and expected that having children was par for the course after I got married. We soon discovered that I had a low ovarian egg reserve and my husband had poor sperm count and quality.
For the next 18 months we went through some of the most challenging moments of our marriage. At times I didn’t think we would stay together. It nearly broke us.
We ended up doing two rounds of in vitro fertilization, more commonly known as IVF. One round was covered by my company’s insurance, but the other was not, since I had exhausted all my benefits with the first round. Throughout our process we received questions from family and friends such as, “How are you paying for this? Isn’t it expensive?” ....

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National Infertility Awareness Week: Inside America's infertility problem


National Infertility Awareness Week: Inside America s infertility problem
CNN
34 mins ago
© Chloe Melas/CNN
Melas is speaking out about her family s struggles.
My husband and I are that one in eight.
When we decided to start our family in 2017, I was 29 years old and expected that having children was par for the course after I got married. We soon discovered that I had a low ovarian egg reserve and my husband had poor sperm count and quality.
For the next 18 months we went through some of the most challenging moments of our marriage. At times I didn t think we would stay together. It nearly broke us. ....

New York , United States , Westchester County , Katy Bell Hendrickson , Ronaldo Perelman , Stefan Radtke Chloe Melas , Barbara Collura , David Schlanger , Kyle Busch , Patty Murray , Samantha Busch , Lisa Lawrence , Katie Lelito , Brianna Keilar , Brian Mazza , Pamela Hirsch , Hellen Gustafson , Chloe Melas , Brian Levine , Bundle Of Joy Fund , Army Special , Department Of Defense , University Of Iowa , National Infertility Awareness Week , Us Department Of Veterans Affairs , University Of Michigan ,

Study identifies major flaws in iBMEC-based models of the blood-brain barrier


Study identifies major flaws in iBMEC-based models of the blood-brain barrier
A type of cell derived from human stem cells that has been widely used for brain research and drug development may have been leading researchers astray for years, according to a study from scientists at Weill Cornell Medicine and Columbia University Irving Medical Center.
The cell, known as an induced Brain Microvascular Endothelial Cell (iBMEC), was first described by other researchers in 2012, and has been used to model the special lining of capillaries in the brain that is called the blood-brain barrier.
Many brain diseases, including brain cancers as well as degenerative and genetic disorders, could be much more treatable if researchers could get drugs across this barrier. For that and other reasons, iBMEC-based models of the barrier have been embraced as an important standard tool in brain research. ....

Tyler Lu , Ronaldo Perelman , David Redmond , Emily Henderson , Columbia University Irving Medical Center , Claudia Cohen Center , Research Specialist , Proceedings Of The National Academy Sciences , Ansary Stem Cell Institute , Memorial Sloan Kettering Cancer Center , Weill Cornell Medicine , Columbia University Irving Medical , Brain Microvascular Endothelial Cell , National Academy , Regenerative Medicine , Weill Cornell , Reproductive Medicine , Study First , Endothelial Cell , Gene Expression , Stem Cells , Transcription Factors , டைலர் லு , ரொனள்டோ பெரல்மேன் , டேவிட் ரெட்மண்ட் , எமிலி ஹென்டர்சன் ,

Weill Cornell researchers detect key flaw in brain modeling


Date Time
Weill Cornell researchers detect key flaw in brain modeling
A type of cell derived from human stem cells that has been widely used for brain research and drug development may have been leading researchers astray for years, according to a study from scientists at Weill Cornell Medicine and Columbia University Irving Medical Center.
Lis Lab/Provided
Induced brain microvascular endothelial cells (IBMECs), top, cultured in 3D assume an epithelial organoid structure and express the epithelial cell marker EPCAM (purple). When they are reprogrammed by overexpression of ETV2, ERG and FLI1, they lose EPCAM expression, acquire vascular markers VE-Cad (red) and PECAM1 (green) and are able to fulfill the function of endothelial cells – forming blood vessels, shown in bottom image. ....

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