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Zenocutuzumab Generates Durable Responses in Advanced NRG1+ NSCLC

Zenocutuzumab elicited clinical activity with a tolerable safety profile in patients with advanced non–small cell lung cancer harboring NRG1 fusions, including those with prior afatinib exposure, according to findings from the ongoing, phase 1/2 eNRGy trial. ....

Memorial Sloan Kettering Cancer Center , New York , United States , Alison Schram , Beigene Springworks , Us Food Drug Administration , Relay Therapeutics , Blueprint Bio , Flagship Pioneering , Redona Therapeutics , Black Diamond Therapeutics , Elevation Oncology , Northern Biologics , Repare Therapeutics , Revolution Medicines , Surface Oncology , Kimd W , Nrg1 Fusions , Phase 1 2 Enrgy Trial , Cla 128 ,