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Zenocutuzumab Generates Durable Responses in Advanced NRG1+ NSCLC

Zenocutuzumab elicited clinical activity with a tolerable safety profile in patients with advanced non–small cell lung cancer harboring NRG1 fusions, including those with prior afatinib exposure, according to findings from the ongoing, phase 1/2 eNRGy trial. ....

Memorial Sloan Kettering Cancer Center , New York , United States , Alison Schram , Beigene Springworks , Us Food Drug Administration , Relay Therapeutics , Blueprint Bio , Flagship Pioneering , Redona Therapeutics , Black Diamond Therapeutics , Elevation Oncology , Northern Biologics , Repare Therapeutics , Revolution Medicines , Surface Oncology , Kimd W , Nrg1 Fusions , Phase 1 2 Enrgy Trial , Cla 128 ,

Merus' Zeno Interim Data Continues to Demonstrate Robust and Durable Responses in NRG1+ Cancer Seite 1

23.10.2023 - - 37% ORR and 14.9 months median DOR in 78 evaluable NRG1+ NSCLC patients - 42% ORR and 9.1 months median DOR in 33 evaluable NRG1+ PDAC patients - Sufficient clinical data expected in 1H24 to support potential BLA submissions UTRECHT, The . Seite 1 ....

United Kingdom , Alison Schram , Andrew Joe , European Society For Medical Oncology , Early Access Program , Memorial Sloan Kettering Cancer Center , Principal Investigator , European Society , Medical Oncology , Chief Medical Officer , Merus Chart , Erus Kurs , Erus Aktie ,