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Immunotherapies Show No Increase in Cancer Recurrence Risk

Patients with immune-mediated diseases and a history of malignancy had similar rates of cancer recurrence whether or not they were receiving immunosuppressive treatments. ....

United States , Dakshita Gupta , Colitis Foundation , Chleck Family Foundation , Massachusetts General Hospital , Clinical Gastroenterology , Chleck Family , Biologic Therapy , Alignant Neoplasia , Meta Analysis , Inflammatory Bowel Disease , Nflammatory Bowel Disease Ibd , Immunosuppressive Therapy , Immunosuppressive Agents , Immunosuppressive Drugs , Rug Immunosuppressive , Clinical Guidelines , Monoclonal Antibody , Rheumatoid Arth ,

Comorbidities Key to Serious Infections With IBD Treatment

Older IBD patients with comorbidities are less likely to be hospitalized due to an infection if they are treated with vedolizumab or ustekinumab than with an anti-TNF agent, suggests a US study. ....

New York , United States , Danaj Lukin , Bharati Kochar , Colitis Foundation , Jill Roberts Center , Chleck Family Foundation , National Institutes Of Health , Theamerican Journal , Massachusetts General Hospital , Medscape Medical News , World Study , Older Adults With , Charlson Comorbidity Index , Inflammatory Bowel Disease , New York City , National Institutes , Chleck Family , Crohns Disease , Anti Tnf , Anti Tumor Necrosis Factor , Biologic Therapy , Ulcerative Colitis , Nflammatory Bowel Disease Ibd , Monoclonal Antibody , Inpatient Care ,

New study predicts how SARS-CoV-2 evades vaccines

Models future SARS-CoV-2 mutations and forecasts their ability to evade immune defenses developed by vaccines and antibody-based treatments ....

Boston University , United States , Amos Hostetter , Jonathan Abraham , Katherine Nabel , National Center , Harvard Pilgrim Health Care Institute , Us Centers For Disease , National Institutes Of Health , Massachusetts Consortium On Pathogen Readiness , Boston University School Of Medicine , Harvard Medical School , Harvard Mit Md Program , Abbvie Bioresearch Center , Chleck Family Foundation , Blavatnik Institute , Translational Science Center , Industry News , South America , Massachusetts General Hospital , Public Health , Boston University School , Abbvie Bioresearch , Massachusetts Consortium , Pathogen Readiness , Disease Control ,

SARS-CoV-2 variants are evolving new ways to evade antibodies, vaccines

This article is part of Harvard Medical School’s continuing coverage of medicine, biomedical research, medical education, and policy related to the ....

Boston University , United States , Amos Hostetter , Jonathan Abraham , Anthony Griffiths , Katherine Nabel , Lindsay Mckay , National Emerging Infectious Diseases Laboratories , National Center , Harvard Pilgrim Health Care Institute , Us Centers For Disease , National Institutes Of Health , Massachusetts Consortium On Pathogen Readiness , Boston University School Of Medicine , Harvard Medical School , Abbvie Bioresearch Center , Chleck Family Foundation , Harvard Mit Program , Blavatnik Institute , Translational Science Center , South America , Phd Program , Massachusetts General Hospital , Public Health , Boston University School , Abbvie Bioresearch ,

Ultrasensitive blood test detects viral protein, confirms vaccine activates robust immune response

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The carefully orchestrated dance between the immune system and the viral proteins that induce immunity against COVID-19 may be more complex than previously thought. A new study by investigators at Brigham and Women s Hospital used an ultrasensitive, single-molecule array (Simoa) assay to detect extremely low levels of molecules in the blood and measured how these levels change over the days and weeks following vaccination. The team found evidence of circulating protein subunits of SARS-CoV-2, followed by evidence of the body mounting its immune response and then clearing the viral protein to below the level of single-molecule detection. Results are published in ....

David Walt , Barbara Hostetter , Alana Ogata , Quanterix Corporation , Wyss Institute , Chleck Family Foundation , Howard Hughes Medical Institute Professor , Women Hospital To Quanterix Corporation , Department Of Pathology , Clinical Infectious , Howard Hughes Medical Institute , Chleck Family , Mass General Brigham , Antigen Detected , Infectious Diseases , டேவிட் வால்ட் , பார்பரா ஹோஸ்டெட்டர் , விஸ் நிறுவனம் , ஹோவர்ட் ஹக்ஸ் மருத்துவ நிறுவனம் ப்ரொஃபெஸர் , துறை ஆஃப் நோயியல் , மருத்துவ தொற்று , ஹோவர்ட் ஹக்ஸ் மருத்துவ நிறுவனம் , நிறை ஜநரல் ப்ரிகாம் , தொற்று நோய்கள் ,