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Keytruda Plus Cabometyx Produces Responses in Cisplatin-Ineligible Bladder Cancer

Frontline treatment with Keytruda and Cabometyx produced responses with a manageable safety profile in patients with cisplatin-ineligible urothelial carcinoma, a type of bladder cancer. ....

United States , Rohitk Jain , Genitourinary Oncology , Moffitt Cancer Center , Bladder Cancer ,

Exelixis, Inc. (NASDAQ:EXEL) Q3 2023 Earnings Call Transcript

Exelixis, Inc. (NASDAQ:EXEL) Q3 2023 Earnings Call Transcript November 1, 2023 Operator: Good day, ladies and gentlemen, and welcome to the Exelixis Third Quarter 2023 Financial Results Conference Call. My name is Gigi, and I’ll be your operator for today. As a reminder, this call is being recorded for replay purposes. I would now like […] ....

Dana Aftab , Amy Peterson , Jennifer Chan , Mike Morrissey , Michael Schmidt , Most Nuclear Weapons , International Kidney Cancer Symposium , Alliance For Clinical Trials , Metastatic Castration Resistant Prostate Cancer , Clinical Trials , Monty Pal , Liver Met , Risk High Reward Businesses , Mike Morrissey , Amy Peterson , Susan Hubbard , Product Development , Commercial Activities , Business Development ,

Selpercatinib Significantly Improves PFS Over MKIs in RET-Mutant Medullary Thyroid Cancer

Selpercatinib demonstrated a statistically significant improvement in progression-free survival vs physician’s choice of cabozantinib or vandetanib in patients with advanced or metastatic RET-mutant medullary thyroid cancer, meeting the primary end point of the phase 3 LIBRETTO-531 trial. ....

Selpercatinib Retevmo , Eli Lilly , Lilly Retevmo , David Hyman , Loxo Oncology , Head Amp Neck Cancers , Precision Medicine In Oncology , Phase 3 Libretto 531 Trial ,

Atezolizumab Plus Cabozantinib Improves PFS in Hormone Therapy–Pretreated mCRPC

The combination of cabozantinib and atezolizumab led to a statistically significant improvement in progression-free survival compared with a second novel hormonal therapy in patients with metastatic castration-resistant prostate cancer and measurable soft tissue disease following 1 prior novel hormonal therapy, meeting one of the primary end points in the primary analysis of the phase 3 CONTACT-02 trial. ....

Howard Mayer , Vickil Goodman , Neeraj Agarwal , University Of Utah , Product Development Medical Affairs , Cancer Research At Huntsman Institute , Presidential Endowed Chair , Cancer Research , Huntsman Cancer Institute , Product Development , Medical Affairs , Immuno Oncology , Prostate Cancer , Metastatic Castration Resistant Prostate Cancer , Phase 3 Contact 02 Trial ,