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Strategy may enable some patients with HER2-positive breast cancer to avoid chemotherapy

Strategy may enable some patients with HER2-positive breast cancer to avoid chemotherapy
healio.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from healio.com Daily Mail and Mail on Sunday newspapers.

United States , Daiichi Sankyo , Javier Cortes , Javier Cort , Bydevin Mclaughlin , Eli Lilly , Devin Mclaughlin , International Breast Cancer Center , Nektar Therapeutics , Merck Sharp , Universidad Europea De Madrid ,

Selinexor maintenance extends PFS in endometrial cancer subgroup with high unmet need

Selinexor maintenance extends PFS in endometrial cancer subgroup with high unmet need
healio.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from healio.com Daily Mail and Mail on Sunday newspapers.

United States , Selinexor Xpovio , Astellas Pharma , Iovance Biotherapeutics , Discussantgini Fleming , Nuvation Bio , Brianm Slomovitz , Bydevin Mclaughlin , Mindy Valcarcel , University Of Chicago , Caris Life Sciences , K Group Beta , Eli Lilly Co , Syros Pharmaceuticals , Mount Sinai Medical Center , Karyopharm Therapeutics , Eli Lilly , Myriad Genetics , Onconova Therapeutics , Physicians Education Resource , Corcept Therapeutics , Cytomx Therapeutics , Molecular Templates , Sermonix Pharmaceutics , Gini Fleming ,

Mirvetuximab soravtansine data 'practice changing' for subset of women with ovarian cancer

CHICAGO — Mirvetuximab soravtansine-gynx extended survival of women with platinum-resistant ovarian cancer and high folate receptor-alpha expression, according to a study that compared the agent with investigator’s choice of chemotherapy.The antibody and microtubule inhibitor conjugate is the first novel therapy to show a survival benefit in a randomized phase 3 study among this ....

United States , Kathleenn Moore , Bydevin Mclaughlin , Daiichi Sankyo Eli Lilly , Maurie Markman , Iovance Biotherapeutics , Mindy Valcarcel , Genentech Roche , Caris Life Sciences , Bristol Myers Squibb , Blueprint Medicines , Clovis Oncology , Eli Lilly , Hengrui Pharmaceutical , Stephenson Cancer Center , Oklahoma College ,

Trastuzumab deruxtecan shows 'broad activity' in HER2-expressing solid tumors

CHICAGO — Trastuzumab deruxtecan showed clinically meaningful activity against several types of HER2-expressing solid tumors, according to interim results of the DESTINY-PanTumor02 study presented at ASCO Annual Meeting.The HER2-directed antibody-drug conjugate, also known as T-DXd (Enhertu; AstraZeneca, Daiichi Sankyo), demonstrated the highest objective response rates and most durable ....

Black Diamond , United States , Tyra Biosciences , Bydevin Mclaughlin , Devin Mclaughlin , Daiichi Sankyo , Bradley Alexander Mcgregor , University Of Texas Md Anderson Cancer Center , Infinity Pharmaceuticals , Menarini Group , Debiopharm Group , Apeiron Biologics , Black Diamond Therapeutics , Karyopharm Therapeutics , Lengo Therapeutics , Loxo Oncology , Oncusp Therapeutics , Silverback Therapeutics , Tallac Therapeutics , Cancer Center , Published June ,

Benefits of ivosidenib regimen for IDH1 -mutant AML increase with longer follow-up

CHICAGO — Ivosidenib extended median OS more than three times longer than placebo when added to azacitidine for adults with treatment-naive, IDH1-mutated acute myeloid leukemia, according to updated results of the phase 3 AGILE trial.The long-term follow-up data, presented at ASCO Annual Meeting, showed an additional 5-month increase in median OS with the ivosidenib (Tibsovo, Servier) ....

United States , Astellas Amgen Biopharama , Mindy Valcarcel , Bydevin Mclaughlin , Bristol Myers Squibb , Gustave Roussy Cancer Center , Jazz Pharmaceuticals , Amgen Biopharama , Auron Therapeutics , Forma Therapeutics , Loxo Oncology , Remix Therapeutics ,