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Benefits of ivosidenib regimen for IDH1 -mutant AML increase with longer follow-up

CHICAGO — Ivosidenib extended median OS more than three times longer than placebo when added to azacitidine for adults with treatment-naive, IDH1-mutated acute myeloid leukemia, according to updated results of the phase 3 AGILE trial.The long-term follow-up data, presented at ASCO Annual Meeting, showed an additional 5-month increase in median OS with the ivosidenib (Tibsovo, Servier) ....

United States , Astellas Amgen Biopharama , Mindy Valcarcel , Bydevin Mclaughlin , Bristol Myers Squibb , Gustave Roussy Cancer Center , Jazz Pharmaceuticals , Amgen Biopharama , Auron Therapeutics , Forma Therapeutics , Loxo Oncology , Remix Therapeutics ,