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Scientists say eye-disease drug may also help fight COVID

Research brief: In a lab study, a UCLA-led team found that verteporfin stopped the replication of SARS-CoV-2, the virus that causes COVID-19. ....

Yunfeng Li , Arjun Deb , Gustavo Garcia Jr , Karin Nielsen Saines , Chandani Sen , Brigitte Gomperts , Sebastian Castillo Cario , Kouki Morizono , Priya Shah , Ashok Kumar , Samuel French , Joseph Irudayam , Arjit Jeyachandran , Shen Li , Arunachalam Ramaiah , Yijie Wang , Vaithilingaraja Arumugaswami , Stem Cell Research , Wayne State University , David Geffen School Of Medicine , National Institutes Of Health , Tata Institute , Research Award Program , Drug Administration , Tata Institute For Genetics , Ucla Wm Keck Foundation ,

Building Robust Collaborations to 'ATTACK' Future Pandemics

Building Robust Collaborations to 'ATTACK' Future Pandemics
ucsd.edu - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from ucsd.edu Daily Mail and Mail on Sunday newspapers.

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First of Its Kind Cystic Fibrosis Gene Expression Atlas Reveals Altered Airway Cells

First of Its Kind Cystic Fibrosis Gene Expression Atlas Reveals Altered Airway Cells
May 10, 2021
Healthy airways (left) show well-defined layers of ciliated cells (green) and basal stem cells (red). In airways affected by cystic fibrosis (right), the layers are disrupted, and scientists identified a transitioning cell type that combines properties of both stem cells and ciliated cells (red and green in the same cell) [Source: UCLA Broad Stem Cell Research Center/Nature Medicine].
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A multi-institute consortium study reports single-cell transcriptomics data that compares cells lining the airways of cystic fibrosis (CF) patients undergoing transplantation for terminal lung disease with that of previously healthy lung donors in a first-of-its-kind molecular atlas. ....

United States , John Mahoney , Brigitte Gomperts , Barry Stripp , Kathrin Plath , Cystic Fibrosis Foundation Therapeutics Lab , Broad Stem Cell Research Center , David Geffen School Of Medicine , University Of Utah , Sinai Board Of Governors Regenerative Medicine Institute , Nature Medicine , Phd Brigitte Gomperts , Stem Cell Research Center , David Geffen School , Molecular Physiology Section , American Physiological Society , Cedars Sinai Board , Governors Regenerative Medicine Institute , ஒன்றுபட்டது மாநிலங்களில் , ஜான் மஹோனி , சிஸ்டிக் ஃபைப்ரோஸிஸ் அடித்தளம் சிகிச்சை ஆய்வகம் , பரந்த தண்டு செல் ஆராய்ச்சி மையம் , டேவிட் கெஃப்ஃபெந் பள்ளி ஆஃப் மருந்து , பல்கலைக்கழகம் ஆஃப் உட்டா , சினை பலகை ஆஃப் கவர்னர்கள் மீளுருவாக்கம் மருந்து நிறுவனம் , இயற்கை மருந்து ,

Molecular analysis identifies key differences in lungs of cystic fibrosis patients

Nature Medicine
Healthy airways (left) show well-defined layers of ciliated cells (green) and basal stem cells (red). In airways affected by cystic fibrosis (right), the layers are disrupted, and scientists identified a transitioning cell type that combines properties of both stem cells and ciliated cells (red and green in the same cell).
A team of researchers from UCLA, Cedars-Sinai and the Cystic Fibrosis Foundation has developed a first-of-its-kind molecular catalog of cells in healthy lungs and the lungs of people with cystic fibrosis.
The catalog, described today in the journal Nature Medicine, reveals new subtypes of cells and illustrates how the disease changes the cellular makeup of the airways. The findings could help scientists in their search for specific cell types that represent prime targets for genetic and cell therapies for cystic fibrosis. ....

Brigitte Gomperts , Barry Stripp , Kathrin Plath , John Jed Mahoney , Gianni Carraro , Justin Langerman , National Cancer Institute , Cystic Fibrosis Foundation , Tumor Cell Biology Training Program , Sinai Board Of Governors Regenerative Medicine Institute , Parkerb Francis Foundation Fellowship , National Heart , Blood Institute , Edythe Broad Center , Stem Cell Research , Cystic Fibrosis Foundation Therapeutics Lab , Broad Stem Cell Research Center , National Institutes Of Health , David Geffen School Of Medicine , Wm Keck Foundation , Disease Research Program , Cystic Fibrosis Foundation Epithelial Stem Cell Consortium , Howard Hughes Medical Institute , Nature Medicine , Regenerative Medicine , Cystic Fibrosis Foundation Therapeutics ,

The Schools of Medicine at Yale and University of Pittsburgh are joining forces with Three Lakes Foundation to accelerate a cure for pulmonary fibrosis

The Schools of Medicine at Yale and University of Pittsburgh are joining forces with Three Lakes Foundation to accelerate a cure for pulmonary fibrosis
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CHICAGO, March 17, 2021 /PRNewswire/ Three Lakes Foundation (TLF) has announced that it has selected Yale University School of Medicine and the University of Pittsburgh School of Medicine to join the
Three Lakes Consortium for Pulmonary Fibrosis (TLC4PF). Together, they will focus on advancing disease understanding with the goal to accelerate new treatments and curing this devastating lung condition.
Naftali Kaminski, MD, Yale School of Medicine and Melanie Königshoff, MD, University of Pittsburgh School of Medicine are joining forces with Three Lakes Foundation ....

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