While the results showed a high prevalence of suspected musculoskeletal symptoms in patients with psoriasis, only a small number were due to psoriatic arthritis.
Usual interstitial pneumonia (UIP) is characterised by a distinctive morphological
and radiological appearance that was considered the pathognomonic hallmark of idiopathic
pulmonary fibrosis (IPF). However, this peculiar lung remodelling pattern is also
seen in other fibrotic interstitial lung diseases, including hypersensitivity pneumonitis,
and connective tissue diseases. In this Personal View, we advocate the designation
of a UIP pattern as a single, discrete diagnostic entity, amalgamating its primary
form and secondary processes in disorders such as hypersensitivity pneumonitis (hypersensitivity
pneumonitis with UIP), rheumatoid arthritis (rheumatoid arthritis with UIP), and others.
Systemic sclerosis, also known as scleroderma, is a rare and complex autoimmune connective-tissue
disease. Once considered an untreatable and unpredictable condition, research advancements
have improved our understanding of its disease pathogenesis and clinical phenotypes
and expanded our treatment armamentarium. Early and accurate diagnosis is essential,
while ongoing efforts to risk stratify patients have a central role in predicting
both organ involvement and disease progression. A holistic approach is required when
choosing the optimal therapeutic strategy, balancing the side-effect profile with
efficacy and tailoring the treatment according to the goals of care of the patient.
DRESS syndrome thelancet.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from thelancet.com Daily Mail and Mail on Sunday newspapers.