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Frontiers | No Association Between Statin Use and the Prognosis of Endometrial Cancer in Women With Type 2 Diabetes


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1PEDEGO Research Unit, Medical Research Center Oulu, Department of Obstetrics and Gynecology, Oulu University Hospital and University of Oulu, Oulu, Finland
2Cancer and Translational Medicine Research Unit, Department of Pathology, Oulu University Hospital and University of Oulu, Oulu, Finland
3Department of Obstetrics and Gynecology, Central Finland Central Hospital, Jyväskylä, Finland
4Department of Oncology, University of Helsinki and Helsinki University Comprehensive Cancer Center, Helsinki, Finland
Preclinical studies have suggested statins have antiproliferative and anti-metastatic effects on endometrial cancer cells. Similarly, most previous epidemiological studies have reported a better prognosis of endometrial cancer in patients who used statins. In this study, we explored the role of statins in the prognosis of endometrial cancer in women with type 2 diabetes in a hospital-based cohort. This retrospective cohort consisted of 119 women with type 2 ....

United States , Ch Ungch Ong Namdo , South Korea , Paijanne Tavastia , San Diego , Satakunta Region , Mellersta Osterbotten , Ha Afon , Kjaer Hansen , Van Arsdale , Mc Menamin , Andrew Tompkins , Bokhman Redux , National Supervisory Authority Of Welfare , Oulu University Hospital , Israeli Gynecologic Oncology Group Study Of Statin , University Hospital Of Oulu , Finnish Medical Society Duodecim , Cancer Genome Atlas Research Network , Finnish Government Research Funds , Graphpad Software , Finnish Society Of Internal Medicine , International Federation Of Gynecology , Advisory Board Of The Finnish Diabetes Society , Aatos Erkko Foundation , Ethics Committee Of Oulu University Hospital ,