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Tree resin could cure infections caused by MRSA bacteria


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Tree resin could cure infections caused by MRSA bacteria
Currently, MRSA is one of the fastest evolving bacteria, causing a wide range of infections from skin disease to serious endocarditis. Researchers at the University of Helsinki created a new biopolymer which kills MRSA nearly 100% upon contact, by combining nanocellulose with compounds derived from tree resin, a side stream from forest industry.
Methicillin-resistant S. aureus (MRSA) is any strain of S. aureus that has developed resistance towards the broad-spectrum β-lactam antibiotics such as cloxacillin, methicillin and flucloxacillin. Various sequelae can result from MRSA infection such as chronic wound infection, sepsis or ventilator-associated pneumonia. MRSA is the leading cause of chronic infections associated to the use of indwelling medical devices. ....

Eteläuomen Läi , Jari Yli Kauhaluoma , Miguel Castanho , Ghada Hassan , University Of Helsinki , University Of Lisbon , Antimicrobial Surfaces , Target Resistant Staphylococcus , Professor Jari Yli Kauhaluoma , Medical Devices , Human Health , மிகுவல் காஸ்டன்ஹோ , காடா ஹாசன் , பல்கலைக்கழகம் ஆஃப் ஹெல்சின்கி , பல்கலைக்கழகம் ஆஃப் லிஸ்பன் , ஆண்டிமைக்ரோபியல் மேற்பரப்புகள் , மருத்துவ சாதனங்கள் , மனிதன் ஆரோக்கியம் , நுண்ணுயிர் எதிர்ப்பிகள் ,

Biotech company founded by University of Toronto researchers secures US$85 million in financing


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Biotech company founded by University of Toronto researchers secures US$85 million in financing
Juan Carlos Zúñiga-Pflücker (left), of the Temerty Faculty of Medicine and Sunnybrook Health Sciences Centre, and Peter Zandstra, who is now at UBC, founded Notch Therapeutics at U of T in 2018.
Notch was founded in 2018 by two pioneers of cell therapy research, Juan Carlos Zúñiga-Pflücker, chair of the department of immunology at the University of Toronto’s Temerty Faculty of Medicine and a senior scientist at Sunnybrook Health Sciences Centre, and Peter Zandstra, who was then at U of T and is now a professor at the University of British Columbia, but continues to collaborate with U of T’s Institute for Biomedical Engineering. The company was supported by MaRS Innovation (now Toronto Innovation Acceleration Partners) and the Centre for Commercialization of Regenerative Medicine. ....

United Kingdom , British Columbia , Juan Carlos , Peter Zandstra , University Of British Columbia , T Institute For Biomedical Engineering , University Of Toronto Temerty Faculty Medicine , Sunnybrook Health Sciences Centre , Centre For Commercialization Of Regenerative Medicine , Notch Therapeutics , Temerty Faculty , Toronto Innovation Acceleration Partners , University Of Toronto , Regenerative Medicine , Cell Therapies , Cell Therapy , Immune Cells , ஒன்றுபட்டது கிஂக்டம் , பிரிட்டிஷ் கொலம்பியா , ஜுவான் கார்லோஸ் , பல்கலைக்கழகம் ஆஃப் பிரிட்டிஷ் கொலம்பியா , டி நிறுவனம் க்கு உயிர் மருத்துவ பொறியியல் , சன்னிபிரூக் ஆரோக்கியம் அறிவியல் மையம் , மையம் க்கு வணிகமயமாக்கல் ஆஃப் மீளுருவாக்கம் மருந்து , உச்சநிலை சிகிச்சை , டொராண்டோ கண்டுபிடிப்பு விரைவுபடுத்துதல் கூட்டாளர்கள் ,

Synthetic "mini" receptors block atherosclerosis


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Synthetic “mini” receptors block atherosclerosis
Atherosclerosis, a lipid-triggered chronic inflammatory disease of our arteries, is the main cause of strokes and heart attacks. An international team of researchers led by the Technical University of Munich (TUM) and the LMU University Hospital has developed novel synthetic peptides that can help to prevent atherosclerosis in vitro, that is in the test tube, as well as in animal models.
Research over the last 20 years has shown that atherosclerosis is a chronic inflammatory condition of the arterial blood vessel wall. Soluble mediators such as cytokines and chemokines are pivotal players in this disease, promoting vascular inflammation. However, the development of anti-inflammatory therapeutics directed against such mediators that could prevent atherosclerosis has proven difficult, despite promising clinical studies in the recent past. ....

Ying Gao , Kathleen Hille , Ozgun Gokce , Sijia Wang , Remco Ta Megens , Chunfang Zan , Simona Gerra , Aphrodite Kapurniotu , Lin Leng , Adrian Hoffmann , Omar El Bounkari , Lars Maegdefessel , Christian Weber , Christine Krammer , Guangyao Yan , Martin Dichgans , Wolfgange Kempf , Markus Brandhofer , Jaroslav Pelisek , Priscila Bourilhon , Hans Henning Eckstein , Dzmitry Sinitski , Richard Bucala , Jessica Pauli , Technical University Of Munich , University Hospital ,