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IU research shows respiratory disease more common than thought - Indianapolis Business Journal

Data analysis by a team of medical professionals across the country indicates primary ciliary dyskinesia, or PCD, is twice as common as previous estimates, occurring in one of about every 7,500 people. ....

Benjamin Gaston , Indiana University School Of Medicine , Indiana University School , Lancet Respiratory Medicine , Finnish European ,

Case Western Reserve and Atelerix Life Sciences Inc. sign option license to develop new therapeutic approach to opioid crisis


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Case Western Reserve and Atelerix Life Sciences Inc. sign option license to develop new therapeutic approach to opioid crisis
Novel small molecule technology reverses life-threatening opioid-induced respiratory depression without diminishing pain relief
Case Western Reserve University and Atelerix Life Sciences Inc., a Charlottesville, Virginia-based biotechnology company, have signed a two-year option to license a novel family of small molecules called Active Thiol-Based Compounds (ATBC’s) to prevent or reverse life-threatening opioid-related side effects.
The lead compound, ATLX-0199 (also called sudaxine), will be first targeted at opioid-induced respiratory depression (OIRD) in the hospital setting.
A recent study by the medical technology company Medtronic found that 46% of surgical patients receiving opioids for post-operative pain-relief suffer one or more episodes of OIRD, presenting perhaps the most significant obstacle to discha ....

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