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IU School of Medicine researchers to present respi

IU School of Medicine researchers to present respi
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California
United-states
San-diego
American
Michaeld-davis
Billie-lou-wood
Benjamin-gaston
Hermanb-wells-center
Indiana-university-school-of-medicine
Atelerix-life-sciences
Department-of-pediatrics
Case-western-reserve-university

Case Western Reserve and Atelerix Life Sciences Inc. sign option license to develop new therapeutic approach to opioid crisis

Date Time Share Case Western Reserve and Atelerix Life Sciences Inc. sign option license to develop new therapeutic approach to opioid crisis Novel small molecule technology reverses life-threatening opioid-induced respiratory depression without diminishing pain relief Case Western Reserve University and Atelerix Life Sciences Inc., a Charlottesville, Virginia-based biotechnology company, have signed a two-year option to license a novel family of small molecules called Active Thiol-Based Compounds (ATBC’s) to prevent or reverse life-threatening opioid-related side effects. The lead compound, ATLX-0199 (also called sudaxine), will be first targeted at opioid-induced respiratory depression (OIRD) in the hospital setting. A recent study by the medical technology company Medtronic found that 46% of surgical patients receiving opioids for post-operative pain-relief suffer one or more episodes of OIRD, presenting perhaps the most significant obstacle to discharge from intensive ca

Charlottesville
Virginia
United-states
James-bates
David-kalergis
Benjamin-gaston
Stephen-lewis
Stephanie-weidenbecher
Case-western-reserve-school-of-medicine
Harrington-discovery-institute-at-university-hospitals
Atelerix-life-sciences
National-institutes-of-health

CWRU, Atelerix sign option license to develop therapeutic approach to opioid crisis

CWRU, Atelerix sign option license to develop therapeutic approach to opioid crisis CWRU, Atelerix sign option license to develop therapeutic approach to opioid crisis Print Case Western Reserve University and Atelerix Life Sciences Inc., a Charlottesville, Va.-based biotechnology company, have signed a two-year option to license novel, small-molecule technology to prevent or reverse life-threatening opioid-related side effects, according to a news release. A recent study by medical technology company Medtronic found that 46% of surgical patients receiving opioids for post-operative pain relief suffer one or more episodes of opioid-induced respiratory depression (OIRD), presenting a significant obstacle to discharging patients from intensive care units and the hospital, the release stated.

James-bates
Benjamin-gaston
Stephen-lewis
Case-western-reserve-school-of-medicine
Harrington-discovery-institute-at-university-hospitals
Atelerix-life-sciences
National-institutes-of-health
Blood-institute-catalyze-program
Technology-transfer-office
University-of-iowa-carver-college-medicine
Department-of-pediatrics
Medtronic

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