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Cadaveric pituitary-derived growth hormone delivery influences iatrogenic Alzheimer's Disease

Recipients of cadaver-derived pituitary growth hormone (c-hGH) developed biomarker changes in the realm of Alzheimer’s disease (AD). ....

Gorodenkoff Shutterstock , Nature Medicine , Iatrogenic Alzheimer , Growth Hormone , Neurodegenerative Diseases ,

Study shows effectiveness of gene therapy in treating congenital deafness

A new study co-led by investigators from Mass Eye and Ear, a member of Mass General Brigham, demonstrated the effectiveness of a gene therapy towards restoring hearing function for children suffering from hereditary deafness. ....

United States , Zheng Yi Chen , Yilai Shu , Association For Research , Hospital Of Fudan University , Hospital Of Fudan University At , Neck Surgery At Harvard Medical School , Mass Eye , Mass General Brigham , Fudan University , Eaton Peabody Laboratories , Neck Surgery , Harvard Medical , Otolaryngology Annual , Gene Therapy , Clinical Trial , Hearing Loss , Medical School , Viral Vector ,

Cancer drug holds promise for shrinking polycystic kidney cysts

Autosomal dominant polycystic kidney disease (ADPKD), the most common form of polycystic kidney disease, can lead to kidney enlargement and eventual loss of function. ....

Bogdan Fedeles , Sakunchai Khumsubdee , Robert Croy , Stefan Somlo , Betsyp Leitch , Sorin Fedeles , Jake Campolo , John Essigmann , Sallys Liu , Denise Andrade , Yale University School Of Medicine , National Institute Of Environmental Health Sciences , Environmental Health Sciences , Proceedings Of The National Academy Sciences , Polycystic Kidney Disease Outcomes Consortium , Us Department Of Defense , Massachusetts Institute Of Technology , Research Scientist Nina Gubina , National Institutes Of Health , Yale University School , National Academy , Biological Engineering , Long Professor , National Institutes , National Institute , Autosomal Dominant Polycystic Kidney Disease ,

Landmark study confirms five key Parkinson's Disease variants in largest meta-analysis

Rare Parkinson’s disease (PD) variants in a large-scale cohort. ....

Npj Parkinson Diseasestudy , Chinnapong Shutterstock , Me Inc , Npj Parkinson , United Kingdom Biobank , Parkinson 39s Disease , Neurodegenerative Disorder ,

Breakthrough study: inhibiting USP30 gene offers hope in treating Parkinson's disease

Whether USP30 inhibition can serve as a disease-modifying therapy for Parkinson's disease (PD). ....

Chinnapong Shutterstock , National Institutes Of Health , Nature Communications , National Institutes , Cellular Thermal Shift Assay , Adeno Associated Virus , Tyrosine Hydroxylase , Arkinson 39s Disease ,